5424-42-0 Usage
General Description
5-(2-Thienyl)-3,4-dihydro-2H-pyrrole, also known as Tiapride, is a chemical compound with a molecular formula of C11H13NS. It is a thienyl-substituted pyrrole derivative that is used as a neuroleptic and antipsychotic medication. Tiapride is used to treat various psychiatric disorders, including schizophrenia, and is also used to alleviate symptoms of alcohol withdrawal and to manage motor and vocal tics associated with Tourette syndrome. It works by modulating the levels of the neurotransmitters dopamine and serotonin in the brain, leading to a reduction in abnormal behaviors and symptoms associated with psychiatric disorders. Additionally, it has minimal sedative and anticholinergic effects, making it a favorable option for patients who cannot tolerate the side effects of other antipsychotic drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 5424-42-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,2 and 4 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5424-42:
(6*5)+(5*4)+(4*2)+(3*4)+(2*4)+(1*2)=80
80 % 10 = 0
So 5424-42-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NS/c1-3-7(9-5-1)8-4-2-6-10-8/h2,4,6H,1,3,5H2
5424-42-0Relevant articles and documents
-
Kirchner,Johns
, p. 2183 (1940)
-
Synthesis of 1-Pyrroline by Denitrogenative Ring Expansion of Cyclobutyl Azides under Thermal Conditions
Ban, Kazuho,Miki, Yuya,Sajiki, Hironao,Sawama, Yoshinari,Tomita, Naohito
, p. 3481 - 3484 (2021/06/17)
We herein report an efficient and systematic synthesis of 1-pyrrolines from cyclobutyl azides under thermal and neutral conditions. The reaction proceeded without any additional reagents, and nitrogen was generated as the sole by-product. Furthermore, the generated 1-pyrrolines could be continuously transformed into pyrroles, N-Boc-amines, and oxaziridines in an one-pot manner. (Figure presented.).
Enantioselective Imine Reduction Catalyzed by Phosphenium Ions
Lundrigan, Travis,Welsh, Erin N.,Hynes, Toren,Tien, Chieh-Hung,Adams, Matt R.,Roy, Kayelani R.,Robertson, Katherine N.,Speed, Alexander W. H.
supporting information, p. 14083 - 14088 (2019/10/11)
The first use of phosphenium cations in asymmetric catalysis is reported. A diazaphosphenium triflate, prepared in two or three steps on a multigram scale from commercially available materials, catalyzes the hydroboration or hydrosilylation of cyclic imin
