54248-71-4

Basic information

• Product Name: 3-phenylimidazo[1,2-b]pyridazine
• Synonyms: 3-phenylimidazo[1,2-b]pyridazine
• CAS NO: 54248-71-4
• Molecular Weight: 195.224
• Mol File: 54248-71-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-phenylimidazo[1,2-b]pyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenylimidazo[1,2-b]pyridazine(54248-71-4)
• EPA Substance Registry System: 3-phenylimidazo[1,2-b]pyridazine(54248-71-4)

Safety Data

• Hazardous Substances Data: 54248-71-4(Hazardous Substances Data)

Upstream product

• 13526-66-4 3-bromo-6-chloro-imidazo[1,2-b]pyridazine 
• 6775-78-6 6-chloroimidazo[1,2-b]pyridazine 
• 18087-73-5 3-bromo-imidazo[1,2-b]pyridazine 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

Synthesis and antifungal activity of imidazo[1,2-b]pyridazine derivatives against phytopathogenic fungi

A series of 3,6-disubstituted imidazo[1,2-b]pyridazine derivatives have been synthesized and characterized with spectroscopic analyses. The antifungal activities of these compounds against nine phytopathogenic fungi were evaluated by the mycelium growth rate method. The in vitro antifungal bioassays indicated that most of compounds displayed excellent and broad-spectrum antifungal activities. Especially, compounds 4a, 4c, 4d, 4l and 4r exhibited 1.9–25.5 fold more potent than the commercially available fungicide hymexazol against Corn Curvalaria Leaf Spot (CL), Alternaria alternate (AA), Pyricularia oryzae (PO) and Alternaria brassicae (AB) strains. Structure-activity relationship analysis showed that the enhanced antifungal activity is significantly affected by the substituents on the benzene ring and pyridazine ring.

TRPC5 INHIBITORS AND METHODS OF USING SAME

Provided herein are TRPC5 inhibitors and methods of using the same, e.g., to protect podocytes and/or treat kidney disease.