54255-74-2

Basic information

• Product Name: N-(2-aminophenyl)-2-chloro-5-nitrobenzamide
• Synonyms: N-(2-aminophenyl)-2-chloro-5-nitrobenzamide
• CAS NO: 54255-74-2
• Molecular Weight: 291.694
• Mol File: 54255-74-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N-(2-aminophenyl)-2-chloro-5-nitrobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-aminophenyl)-2-chloro-5-nitrobenzamide(54255-74-2)
• EPA Substance Registry System: N-(2-aminophenyl)-2-chloro-5-nitrobenzamide(54255-74-2)

Safety Data

• Hazardous Substances Data: 54255-74-2(Hazardous Substances Data)

Upstream product

• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 25784-91-2 2-chloro-5-nitrobenzoylchloride 
• 146651-75-4 tert–butyl (2–aminophenyl)carbamate 
• 95-54-5 1,2-diamino-benzene 

Downstream Products

• 54255-79-7 2-(2-chloro-5-nitrophenyl)-1H-benzo[d]imidazole 
• 313402-16-3 3-(1H-benzo[d]imidazol-2-yl)-4-chloroaniline 

Relevant articles and documents

Covalent Occlusion of the RORγt Ligand Binding Pocket Allows Unambiguous Targeting of an Allosteric Site

The nuclear receptor RORγt is a key positive regulator in the differentiation and proliferation of T helper 17 (Th17) cells and the production of proinflammatory cytokines like IL-17a. Dysregulation of this pathway can result in the development of various

Comprising benzimidazole structure of sulfonamide derivatives and its preparation and use

The invention belongs to the field of medical technology, discloses benzimidazole structure of sulfonamide derivatives and its preparation method and application. The derivatives of formula I as shown in the structural formula, in formula I, R1 , R2 , R3 , R4 , X such as the claim and the specification. The compounds of the invention has better anti-tumor activity, can be used as a therapeutic agent for the treatment of tumor, it is also SMO inhibitors. (Type I).

Nicotinamide derivative and preparation method and application thereof

The invention discloses a novel compound N-3-(4-R2 substituted)-(1-R-substituted benzimidazole)-(1'-R3 substituted)-2'-oxa-nicotinamide derivative, and a preparation method and an application thereof.The structural formula of the compound is as shown in a formula I, in which R1, R2 and R3 are described in the claims and description. The compound has very good anti-diabetes activity, and can be used as therapeutic agent for treating diabetes in the field of preparing anti-diabetes drugs. The formula is as shown in the description.