54277-08-6

Basic information

• Product Name: meso-1,4-diphenyl-but-2-yne-1,4-diol
• Synonyms: meso-1,4-diphenyl-but-2-yne-1,4-diol
• CAS NO: 54277-08-6
• Molecular Weight: 238.286
• Mol File: 54277-08-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: meso-1,4-diphenyl-but-2-yne-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: meso-1,4-diphenyl-but-2-yne-1,4-diol(54277-08-6)
• EPA Substance Registry System: meso-1,4-diphenyl-but-2-yne-1,4-diol(54277-08-6)

Safety Data

• Hazardous Substances Data: 54277-08-6(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 4187-87-5 (R)-1-phenyl-2-propyn-1-ol 
• 925-90-6 ethylmagnesium bromide 
• 1087-09-8 1,4-diphenyl-but-2-yne-1,4-dione 
• 4187-87-5 1-phenylprop-2-yn-1-ol 
• 4482-17-1 (S:S)-1.4-diphenyl-butyne-⁽²⁾-diol-(1.4) 
• 749269-14-5 (R,R)-diphenylbut-2-yne-1,4-diol 

Downstream Products

• 1087-09-8 1,4-diphenyl-but-2-yne-1,4-dione 
• 13401-42-8 (1R,4S)-1,4-diphenylbutane-1,4-diol 
• 23637-57-2 (Z)-1,4-diphenylbut-2-ene-1,4-diol 
• 63787-80-4 meso-1,4-dimethoxy-1,4-diphenyl-but-2-yne 
• 749269-24-7 (1R,2E,4S)-2,3-dibromo-1,4-diphenylbut-2-ene-1,4-diol 
• 107538-22-7 meso-1.4-diphenyl-butene-(2t)-diol-(1.4) 
• 107487-46-7 (RS,SR)-4-methoxy-1,4-diphenylbut-2-yn-1-ol 
• 144-62-7 oxalic acid 
• 65-85-0 benzoic acid 
• 886-65-7 trans,trans-1,4-Diphenyl-1,3-butadiene 
• 1030-09-7 (E)-(RS,SR)-4-methoxy-1,4-diphenylbut-2-en-1-ol 
• 959-27-3 (Z)-1,4-diphenylbut-2-ene-1,4-dione 
• 32673-77-1 meso-1,4-dimethoxy-1,4-diphenyl-butane 
• 128237-82-1 meso-1,4-dimethoxy-1,4-diphenyl-but-2ξ-ene 

Relevant articles and documents

Highly Stereoselective approach to Alk-2-yne-1,4-diols by oxazaborolidine-mediated reduction of Alk-2-yne-1,4-diones

We performed the borane-mediated reduction of a series of symmetrical alk-2-yne-1,4-diones (5) in the presence of the oxazaborolidine (R)-6 to afford (R,R)-alk-2-yne-1,4-diols ((R,R)-1) in good yields and high stereoselectivities (up to 99.9% ee). In some cases, the stereochemical purity of 1 was improved by a two-step process: (i) temporary transformation of 1 into its vic-dibromo derivatives 9, which allowed us to remove the minor meso isomer by chromatography, and (ii) regeneration of the enantioenriched diols 1 with SmI2. Reduction of the hexacarbonyldicobalt complexes 8 derived from 5 was also successful.