543-83-9 Usage
General Description
Galegine is an alkaloid compound found in various plants, including Galega officinalis and other members of the Fabaceae family. It has been identified as a potential anti-diabetic agent, as it is able to lower blood sugar levels in animal models. Galegine functions by inhibiting the enzyme glucose-6-phosphatase, which reduces the production of glucose in the liver and consequently lowers blood sugar levels. However, galegine has been found to have toxic effects in high doses, particularly on the liver and kidneys. As a result, the use of galegine as a therapeutic agent is limited, but it remains a subject of study in the field of natural products and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 543-83-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 543-83:
(5*5)+(4*4)+(3*3)+(2*8)+(1*3)=69
69 % 10 = 9
So 543-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H13N3/c1-5(2)3-4-9-6(7)8/h3H,4H2,1-2H3,(H4,7,8,9)
543-83-9Relevant articles and documents
Novel hypotensive agents from Verbesina caracasana. 8. Synthesis and pharmacology of (3,4-dimethoxycinnamoyl)-N1-agmatine and synthetic analogues
Carmignani,Volpe,Botta,Espinal,De Bonnevaux,De Luca,Botta,Corelli,Tafi,Sacco,Delle Monache
, p. 2950 - 2958 (2007/10/03)
The more polar metabolites from the Venezuelan plant Verbesina caracasana, i.e., N3-prenylagmatine, (3,4-dimethoxycinnamoyl)-N1-agmatine, agmatine, and galegine (prenylguanidine), previously reported (Delle Monache, G.; et al. BioMed
