54328-33-5 Usage
Description
Chondroitin sulfate B sodium salt, also known as dermatan sulfate, is a glycosaminoglycan (GAG) that is a polysaccharide chain composed of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA). It can be sulfated on either or both GalNAc and GlcA units. Chondroitin sulfate B is a component of proteoglycans such as decorin, biglycan, and versican, and is involved in various biological processes.
Uses
Used in Pharmaceutical Industry:
Chondroitin sulfate B sodium salt is used as an antithrombotic agent for preventing blood clot formation. It is also used to study its roles as a biomolecule receptor, mediator of cell signaling, and cell binding molecule.
Used in Research and Development:
Chondroitin sulfate B sodium salt is used as a research tool to compare its properties to those of chondroitin sulfate A and chondroitin sulfate C. It is also used to study the cytotoxicity of β peptide (1-42).
Used in Drug Delivery Systems:
Chondroitin sulfate B sodium salt can be used in the development of drug delivery systems, potentially enhancing the delivery, bioavailability, and therapeutic outcomes of various drugs.
Chemical Properties:
Chondroitin sulfate B sodium salt is also available in fractionated forms with average molecular weights of 25,000 ± 2,500 and 50,000 ± 5,000, along with different Anti-Xa and Anti-IIa activities. These properties can be tailored to specific applications and requirements.
Purification Methods
Dermatan sulfate is purified by digestion with papain and hyaluronidase, and fractionation using aqueous EtOH. [Gifonelli & Roden Biochemical Preparations 12 1 1968.]
Check Digit Verification of cas no
The CAS Registry Mumber 54328-33-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,3,2 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 54328-33:
(7*5)+(6*4)+(5*3)+(4*2)+(3*8)+(2*3)+(1*3)=115
115 % 10 = 5
So 54328-33-5 is a valid CAS Registry Number.
