5436-58-8

Basic information

• Product Name: Benzeneacetic acid, 1-Methylpropyl ester
• Synonyms: Benzeneacetic acid, 1-Methylpropyl ester
• CAS NO: 5436-58-8
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.25424
• Mol File: 5436-58-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 256.6°Cat760mmHg
• Flash Point: 100.7°C
• Appearance: /
• Density: 1g/cm³
• CAS DataBase Reference: Benzeneacetic acid, 1-Methylpropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 1-Methylpropyl ester(5436-58-8)
• EPA Substance Registry System: Benzeneacetic acid, 1-Methylpropyl ester(5436-58-8)

Safety Data

• Hazardous Substances Data: 5436-58-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 5382, 1983 DOI: 10.1021/jo00174a052Tetrahedron Letters, 26, p. 5743, 1985

Upstream product

• 201230-82-2 carbon monoxide 
• 27992-27-4 sodium 2-benzylidene-1-tosylhydrazin-1-ide 
• 78-92-2 iso-butanol 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 103-82-2 phenylacetic acid 
• 22238-17-1 tri-sec-butylborate 
• 100-44-7 benzyl chloride 
• 536-74-3 phenylacetylene 
• 78-76-2 s-butyl bromide 
• 100-39-0 benzyl bromide 
• 2269-22-9 aluminum tri-sec-butoxide 
• 6863-58-7 di-2-butyl ether 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 7631-42-7 phenylacetic acid anion 
• 78-92-2 iso-butanol 
• 126309-16-8 C₁₂H₁₅FO₂ 
• 1578-63-8 d'acide 2-fluoro-2-phenyl acetique 
• 360-03-2 2,2-Difluoro-2-phenylacetic acid 
• 38018-73-4 Di-sec-butyl-α-butyl-α'-phenylsuccinat 
• 38018-71-2 sec-Butyl-α-phenylacrylat 
• 38018-74-5 Di-sec-butyl-α-butyl-α-phenylsuccinat 
• 38018-76-7 sec-Butyl-2-phenylhexanoat 
• 38018-75-6 Di-sec-butyl-phenylsuccinat 

Relevant articles and documents

[Co(MeTAA)] Metalloradical Catalytic Route to Ketenes via Carbonylation of Carbene Radicals

An efficient synthetic strategy towards beta-lactams, amides, and esters involving “in situ” generation of ketenes and subsequent trapping with nucleophiles is presented. Carbonylation of carbene radical intermediates using the cheap and highly active cobalt(II) tetramethyltetraaza[14]annulene catalyst [Co(MeTAA)] provides a convenient one-pot synthetic protocol towards substituted ketenes. N-tosylhydrazones are used as carbene precursors, thereby bridging the gap between aldehydes and ketenes. Activation of these carbene precursors by the metalloradical cobalt(II) catalyst affords CoIII-carbene radicals, which subsequently react with carbon monoxide to form ketenes. In the presence of a nucleophile (imine, alcohol, or amine) in the reaction medium the ketene is immediately trapped, resulting in the desired products in a one-pot synthetic protocol. The β-lactams formed upon reaction with imines are produced in a highly trans-selective manner.

Oxidation of Alkynes by Hydrogen Peroxide Catalyzed by Methylrhenium Trioxide

The oxidation of alkynes with hydrogen peroxide is catalyzed by methylrhenium tioxide.The reactions can be rationalized by postulating that an oxirene intermediate is formed between a rhenium peroxide and the alkyne.Internal alkynes yield α-diketones and carboxylic acids, the latter from the complete cleavage of the triple bonds.Rearrangement products were observed only for aliphatic alkynes.Terminal alkynes gave carboxylic acids and their derivatives and α-keto acids as the major products, but their yields varied with the solvent used.

RHODIUM(I) CATALYZED CARBONYLATION REACTIONS OF HALIDES AND ETHERS

Benzylic bromides and methyl ioide react with ethers, carbon monoxide, potassium iodide, and the dimer of chloro(1,5-hexadiene)rhodium(I) to give esters in good yields.