54362-71-9

Basic information

• Product Name: l-Alminoprofen
• Synonyms: l-Alminoprofen;(-)-2-(p-((2-Methylallyl)amino)phenyl)propionic acid;Benzeneacetic acid, alpha-methyl-4-((2-methyl-2-propenyl)amino)-, (-)-;Propionic acid, 2-(4-(methallylamino)phenyl)-, (-)-;Benzeneacetic acid, α-methyl-4-[(2-methyl-2-propenyl)amino]-, (-)-
• CAS NO: 54362-71-9
• Molecular Formula: C₁₃H₁₇NO₂
• Molecular Weight: 219.27958
• Mol File: 54362-71-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: l-Alminoprofen(CAS DataBase Reference)
• NIST Chemistry Reference: l-Alminoprofen(54362-71-9)
• EPA Substance Registry System: l-Alminoprofen(54362-71-9)

Safety Data

• Hazardous Substances Data: 54362-71-9(Hazardous Substances Data)

Upstream product

• 362052-00-4 2-(4-cyano-phenyl)-propionic acid 

Relevant articles and documents

Boryl Radical Activation of Benzylic C-OH Bond: Cross-Electrophile Coupling of Free Alcohols and CO2via Photoredox Catalysis

A new strategy for the direct cleavage of the C(sp3)-OH bond has been developed via activation of free alcohols with neutral diphenyl boryl radical generated from sodium tetraphenylborate under mild visible light photoredox conditions. This strategy has been verified by cross-electrophile coupling of free alcohols and carbon dioxide for the synthesis of carboxylic acids. Direct transformation of a range of primary, secondary, and tertiary benzyl alcohols to acids has been achieved. Control experiments and computational studies indicate that activation of alcohols with neutral boryl radical undergoes homolysis of the C(sp3)-OH bond, generating alkyl radicals. After reducing the alkyl radical into carbon anion under photoredox conditions, the following carboxylation with CO2 affords the coupling product.

Phenylacetic acid derivatives

The present invention relates to phenylacetic acid derivatives having the general formula: SPC1 In which R1 represents a lower alkyl radical, a lower alkenyl radical, a lower alkynyl radical or an aryl(lower) alkyl radical, R2 represents hydrogen or a methyl radical, their esters and their salts with bases and acids. Said derivatives have in particular an analgesic and/or anti-inflammatory activity.