54382-73-9

Basic information

• Product Name: (+/-)-COREY LACTONE, 5-(4-PHENYLBENZOATE)
• Synonyms: (3ARS,4SR,5RS,6ASR)-HEXAHYDRO-4-HYDROXYMETHYL-5-(4-PHENYLBENZOYLOXY)CYCLOPENTA[B]FURAN-2-ONE;(+/-)-COREY LACTONE, 5-(4-PHENYLBENZOATE);(3aRS,4RS,5RS,6aRS)-Hexahydro-4-hydroxymethyl-5-(4-phenylbenzyloxy)cyclopenta[b]furan-2-one;(n)-corey lactone, 5-(4-phenylbenzoate);RACEMIC COREY LACTONE P-PHENYLBENZOATE ALCOHOL;(3aR,4S,5R,6aS)-Hexahydro-4-hydroxymethyl-5-(4-phenylbenzyloxy)cyclopenta[b]furan-2-one;phenylbenzoyloxy)cyclopenta[b]furan-2-one;[(3aR,4S,5R,6aS)-4-(hydroxymethyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] 4-phenylbenzoate
• CAS NO: 54382-73-9
• Molecular Formula: C₂₁H₂₀O₅
• Molecular Weight: 352.38
• Product Categories: API
• Mol File: 54382-73-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 149-151°C
• Appearance: /
• Density: 1.32
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (+/-)-COREY LACTONE, 5-(4-PHENYLBENZOATE)(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-COREY LACTONE, 5-(4-PHENYLBENZOATE)(54382-73-9)
• EPA Substance Registry System: (+/-)-COREY LACTONE, 5-(4-PHENYLBENZOATE)(54382-73-9)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 54382-73-9(Hazardous Substances Data)

Usage

Description

(+/-)-COREY LACTONE, 5-(4-PHENYLBENZOATE) is a chemical compound with a unique structure that has been identified for its potential applications in various fields, particularly in biological studies and pharmaceutical research. It is characterized by its ability to interact with specific biological targets, making it a valuable tool for the development of new therapeutic agents.

Uses

Used in Pharmaceutical Research:
(+/-)-COREY LACTONE, 5-(4-PHENYLBENZOATE) is used as a research compound for the identification of novel mammalian squalene synthase inhibitors. This application is significant because squalene synthase is an essential enzyme in the biosynthesis of cholesterol, and its inhibition can lead to the development of new drugs for the treatment of hypercholesterolemia and other cholesterol-related conditions.
Used in Biological Studies:
In the field of biological studies, (+/-)-COREY LACTONE, 5-(4-PHENYLBENZOATE) serves as a valuable tool for understanding the mechanisms of various biological processes. Its use in 3D-pharmacophore modeling allows researchers to predict the interactions between the compound and its target proteins, which can be crucial in the design of new drugs with improved efficacy and selectivity.
Overall, (+/-)-COREY LACTONE, 5-(4-PHENYLBENZOATE) is a versatile compound with potential applications in pharmaceutical research and biological studies, making it an important asset in the development of new therapeutic agents and the advancement of our understanding of biological processes.

Upstream product

• 62939-85-9 (+/-)-7α-hydroxy-2-oxa-6β-triphenylmethoxymethyl-cis-bicyclo[3.3.0]octan-3-one 
• 90156-85-7 7α-formyloxy-8β-formyloxymethylene-cis-2-oxabicyclo<3.3.0>octan-3-one 
• 54423-47-1 (+/-)-(3aα,4α,5β,6aα)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopentafuran-2-one 
• 26054-46-6 cis-(±)-2-oxabicyclo[3.3.0]oct-6-en-3-one 
• 62939-81-5 Biphenyl-4-carboxylic acid (3aS,4R,5S,6aR)-2-oxo-4-trityloxymethyl-hexahydro-cyclopenta[b]furan-5-yl ester 

Downstream Products

• 39265-57-1 <3aS(3aα,4α,5β,6aα)>-(+)-5-(1,1'-biphenyl-4-carbonyloxy)hexahydro-4-hydroxymethyl-2H-cyclopentafuran-2-one 
• 143400-00-4 (1S,2R,3S,4R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-2-(2-[1,3]dithian-2-ylidene-ethyl)-4-(tetrahydro-pyran-2-yloxy)-cyclopentanol 
• 143400-01-5 (1SR,5RS,6SR,7RS)-(+/-)-7'-<(1,1-dimethylethyl)diphenylsilyloxymethyl>-8'-(tetrahydro-2H-pyran-2-yloxy)spiro<1,3-dithian-2,3'-<2>oxabicyclo<4.3.0>nonane> 
• 87858-95-5 (1SR,5RS,6SR,7RS)-(+/-)-6-<(1,1-dimethylethyl)diphenylsilyloxymethyl>-7-hydroxy-2-oxabicyclo<3.3.0>octane-3-one 
• 143399-99-9 (1SR,5RS,6SR,7RS)-(+/-)-7-<(4-biphenyl)carbonyloxy>-6-<(1,1-dimethylethyl)diphenylsilyloxy>methyl-2-oxabicyclo<3.3.0>octane-3-one 
• 31752-99-5 (-)-Corey lactone 5-(4-phenylbenzoate) 
• 127783-76-0 <3aS(2aα,4α,5β,6aα)>-(+)-5-(1,1'-biphenyl-4-carbonyloxy)-4-(butyryloxymethyl)hexahydro-2H-cyclopentafuran-2-one 
• 118560-20-6 <3aR,S(3aα,4α,5β,6aα)>-(+/-)-<5-(1,1'-biphenyl-4-carbonyloxy)hexahydro-2H-cyclopentafuran-2-on-4-yl>methyl hydrogen pentanedioate 
• 118560-19-3 <3aR,S(3aα,4α,5β,6aα)>-(+/-)-<5-(1,1'-biphenyl-4-carbonyloxy)hexahydro-2H-cyclopentafuran-2-on-4-yl>methyl hydrogen butanedioate 

Relevant articles and documents

7α-FORMYLOXY-8β-FORMYLOXYMETHYLENE-cis-2-OXABICYCLOOCTAN-3-ONE AS A USEFUL SYNTHON FOR PROSTAGLANDINS

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