54393-21-4

Basic information

• Product Name: (Z)-3-AMino-2-Methyl-2-butenoic Acid Ethyl Ester
• Synonyms: (Z)-3-AMino-2-Methyl-2-butenoic Acid Ethyl Ester;(2Z)-3-AMino-2-Methyl-2-butenoic Acid Ethyl Ester
• CAS NO: 54393-21-4
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143
• Product Categories: Miscellaneous Reagents
• Mol File: 54393-21-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: (Z)-3-AMino-2-Methyl-2-butenoic Acid Ethyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-AMino-2-Methyl-2-butenoic Acid Ethyl Ester(54393-21-4)
• EPA Substance Registry System: (Z)-3-AMino-2-Methyl-2-butenoic Acid Ethyl Ester(54393-21-4)

Safety Data

• Hazardous Substances Data: 54393-21-4(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Upstream product

• 626-34-6 ethyl 3-aminobut-2-enoate 
• 74-88-4 methyl iodide 
• 609-14-3 2-acetylpropanoic acid ethyl ester 

Downstream Products

• 108137-73-1 (Z)-3-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylamino)-2-methyl-but-2-enoic acid ethyl ester 
• 102644-77-9 (Z)-2-Methyl-3-(3-phenyl-ureido)-but-2-enoic acid ethyl ester 
• 102626-11-9 5,6-dimethyl-3-phenyl-2-thioxo-1H-pyrimidin-4-one 
• 109371-16-6 4-hydroxy-3,5,6-trimethyl-2(1H)-pyridone 
• 77629-51-7 Ethyl 2,4-Dihydroxy-5,6-dimethylnicotinate 
• 77629-51-7 4-hydroxy-5,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid ethyl ester 
• 936744-52-4 2,5,6-trimethyl-3-phenylpyrimidin-4(3H)-one 
• 85721-33-1 ciprofloxacin 
• 640721-52-4 4-bromo-2-methoxy-5,6-dimethylpyridin-3-amine 
• 640721-49-9 4-bromo-5,6-dimethyl-2(1H)-pyridinone 
• 84953-72-0 4-hydroxy-5,6-dimethylpyridin-2(1H)-one 
• 640721-50-2 4-bromo-6-methoxy-2,3-dimethylpyridine 

Relevant articles and documents

Compounds for modulating TRPV3 function

The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.

Enantioselective hydrogenation of tetrasubstituted olefins of cyclic β-(acylamino)acrylates

Hydrogenation of a series of cyclic β-(acylamino)acrylates with tetrasubstituted olefins has been accomplished successfully with the use of Ru catalysts with chiral biaryl ligands such as C3-TunaPhos, and up to over 99% ee's have been achieved. This methodology provides an efficient catalytic method for the synthesis of both cis and trans chiral cyclic β-amino acid derivatives. Copyright

Steric and Conformational Effects in Nicotine Chemistry

The stereoselectivity of iodomethylation of nicotine and seven nicotine analogues having pyridine alkyl groups was determined by using 13C NMR.Alkylation at the pyridine (N) and at the pyrrolidine (N') nitrogens was observed.Two modes of N'-iodomethylation occur, cis and trans to the pyridine ring.N'-Iodomethylation occurs regioselectively cis to the pyridine ring for all compounds examined.The N/N' and N'cis/N'trans ratios for the nicotinoids were evaluated with regard to (1) the orientation of the N'-methyl group in the free base, (2) conformational properties of the pyridine ring with respect to the pyrrolidine ring, and (3) steric hindrance and buttressing effects on the pyridine nitrogen.The Curtin-Hammett principle and the Winstein-Holness equation are used to analyse reactions.