54430-64-7

Basic information

• Product Name: [(1S)-2-imidazol-1-yl-1-methyl-2-oxo-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 54430-64-7
• Molecular Weight: 239.274
• Mol File: 54430-64-7.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: [(1S)-2-imidazol-1-yl-1-methyl-2-oxo-ethyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(1S)-2-imidazol-1-yl-1-methyl-2-oxo-ethyl]-carbamic acid tert-butyl ester(54430-64-7)
• EPA Substance Registry System: [(1S)-2-imidazol-1-yl-1-methyl-2-oxo-ethyl]-carbamic acid tert-butyl ester(54430-64-7)

Safety Data

• Hazardous Substances Data: 54430-64-7(Hazardous Substances Data)

Upstream product

• 288-32-4 1H-imidazole 
• 2483-49-0 tert-butyloxycarbonyl-L-alanine p-nitrophenyl ester 
• 15761-38-3 L-N-Boc-Ala 
• 6160-65-2 1,1'-Thiocarbonyldiimidazole 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 288-32-4 1H-imidazole 
• 2483-49-0 tert-butyloxycarbonyl-L-alanine p-nitrophenyl ester 
• 163659-02-7 (4S,1'S)-1-benzyl-4-(1-tert-butoxycarbonylamino)-2-pyrrolidone 
• 163659-25-4 (4R,1'S)-1-benzyl-4-(1-tert-butoxycarbonylamino)-2-pyrrolidone 
• 198955-57-6 ((S)-3-Benzylcarbamoyl-3,3-difluoro-2-hydroxy-1-methyl-propyl)-carbamic acid tert-butyl ester 
• 218953-26-5 2-(2-tert-butoxycarbonylaminopropionyl)heptanedioic acid 7-ethylester 1-methyl ester 
• 867325-96-0 benzyl-[(1S)-2-(dimethylphenylsilanyl)-1-methylallyl]-carbamic acid tert-butyl ester 
• 867325-92-6 [(1S)-2-(dimethylphenylsilanyl)-1-methylallyl]-carbamic acid tert-butyl ester 
• 867325-88-0 [(1S)-2-(dimethylphenylsilanyl)-1-methyl-2-oxo-ethyl]-carbamic acid tert-butyl ester 
• 187806-88-8 phenylmethyl (4S)-4-(t-butyloxycarbonyl)amino-3-oxopentanoate 
• 146553-06-2 tert-butyl {(S)-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate 
• 101669-78-7 methyl (S)-4-[(tert-butoxycarbonyl)amino]-3-oxopentanoate 
• 41938-15-2 methyl (tert-butoxycarbonyl)-L-alanyl-L-threoninate 

Relevant articles and documents

AMINOACYL DERIVATIVES OF NUCLEOSIDES, NUCLEOTIDES, AND POLYNUCLEOTIDES 17. POSSIBLE USE OF N,N'-THIOCARBONYLDIIMIDAZOLE FOR SYNTHESIS OF 2'(3')-O-AMINOACYLNUCLEOTIDES

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N-carbamate protected amino acid derived guanidine organocatalysts

We report the preparation of a range of N-protected amino acid derived guanidine organocatalysts and their application to the Michael addition of 2-hydroxy-1,4-napthoquinone to β-nitrostyrene, achieving a maximum ee of 26%. Whilst these catalysts gave poo

Synthesis and preliminary biological evaluations of (+)-isocampholenic acid-derived amides

The synthesis of two novel (+)-isocampholenic acid-derived amines has been realized starting from commercially available (1S)-(+)-10-camphorsulfonic acid. The novel amines as well as (+)-isocampholenic acid have been used as building blocks in the constru

Cu(I)-catalyzed [3+2] cycloadditions of tert-butyl (S)-(3-oxopent-4-yn-2- yl)carbamate to 1-benzylidenepyrazole-3-one-derived azomethine imines

Parallel screening of suitable reaction conditions for Cu(I)-catalyzed [3+2] cycloadditions of (1Z,4R*,5R*)-4- benzoylamino-1-benzylidene-5-phenyl-3-oxopyrazolidin-1-ium-2-ide (1a) to methyl propiolate (2) has established that this reaction proceeds smoothly at room temperature in acetonitrile in the presence of CuI and Huenig's base. The optimized reaction conditions were then applied in regio- and stereo-selective 1,3-dipolar cycloadditions of racemic azomethine imines 1a-e to tert-butyl (S)-(3-oxopent-4-yn-2-yl)carbamate (6) leading to mixtures of diastereomeric non-racemic chromatographically separable cycloadducts 7a-d, 7′ a-d, 8e, and 8′e. The structures of the products were confirmed by NMR spectroscopy.