544434-65-3

Basic information

• Product Name: (2S,3S)-2-Amino-3-benzyloxy-succinic acid 1-(7-methoxy-2-oxo-2H-chromen-4-ylmethyl) ester
• CAS NO: 544434-65-3
• Molecular Weight: 427.411
• Mol File: 544434-65-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S)-2-Amino-3-benzyloxy-succinic acid 1-(7-methoxy-2-oxo-2H-chromen-4-ylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-2-Amino-3-benzyloxy-succinic acid 1-(7-methoxy-2-oxo-2H-chromen-4-ylmethyl) ester(544434-65-3)
• EPA Substance Registry System: (2S,3S)-2-Amino-3-benzyloxy-succinic acid 1-(7-methoxy-2-oxo-2H-chromen-4-ylmethyl) ester(544434-65-3)

Safety Data

• Hazardous Substances Data: 544434-65-3(Hazardous Substances Data)

Upstream product

• 84471-16-9 4-(diazomethyl)-7-methoxycoumarin 

Downstream Products

• 72433-26-2 6-methoxy-1-hydroxymethyl-3-oxo-3H-benzopyran 
• 205309-81-5 L-threo-β-oxybenzylaspartic acid 

Relevant articles and documents

Synthesis and photoreactivity of caged blockers for glutamate transporters

L-TBOA (L-threo-β-benzyloxyaspartate) is, so far, the most potent non-transportable blocker for glutamate transporters. We synthesized α-CMCM-L-TBOA (1a) possessing [7-(carboxymethoxy)coumarin-4-yl]methyl ester as a caging group. α-CMCM-L-TBOA (1a) is biologically inactive until UV irradiation and the photolysis of 1a immediately released L-TBOA to show glutamate uptake inhibition. The photoreactivity of the coumarin-type caging group was superior to that of the o-nitrobenzyl-type caging group.