54453-91-7Relevant articles and documents
Process for making 2-bromopyridine
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, (2008/06/13)
Disclosed is the improvement to the Craig process for producing 2-bromopyridine by the diazotization-bromination reaction of 2-aminopyridine with HBr in the presence of Br2 and a diazotization agent wherein the improvement is to conduct the reaction in the additional presence of H2 SO4 and to employ a molar ratio of HBr:2-aminopyridine in the range from about 1:1 to about 3.5:1 and to employ a molar ratio of H2 SO4 :HBr in the range from about 2:8 to about 8:2.