544693-01-8

Basic information

• Product Name: 4-[6-Chloro-2-(2-(pyridin-2-yl)ethoxy)pyriMidin-4-yl]Morpholine
• Synonyms: 4-[6-Chloro-2-(2-(pyridin-2-yl)ethoxy)pyriMidin-4-yl]Morpholine
• CAS NO: 544693-01-8
• Molecular Formula: C₁₅H₁₇ClN₄O₂
• Molecular Weight: 320.77408
• Product Categories: Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 544693-01-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 532.97°C at 760 mmHg
• Flash Point: 276.131°C
• Appearance: /
• Density: 1.306g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.591
• Solubility: Dichloromethane, Dimethylformamide, Dioxane, Ethyl Acetate
• CAS DataBase Reference: 4-[6-Chloro-2-(2-(pyridin-2-yl)ethoxy)pyriMidin-4-yl]Morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[6-Chloro-2-(2-(pyridin-2-yl)ethoxy)pyriMidin-4-yl]Morpholine(544693-01-8)
• EPA Substance Registry System: 4-[6-Chloro-2-(2-(pyridin-2-yl)ethoxy)pyriMidin-4-yl]Morpholine(544693-01-8)

Safety Data

• Hazardous Substances Data: 544693-01-8(Hazardous Substances Data)

Usage

Description

4-[6-Chloro-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl]Morpholine is a chemical compound characterized by its white solid appearance. It is an intermediate in the synthesis of trisubstituted pyrimidine compounds, which are known for their diverse range of applications in various industries.

Uses

Used in Pharmaceutical Industry:
4-[6-Chloro-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl]Morpholine is used as an intermediate for the preparation of trisubstituted pyrimidine compounds. These compounds are known for their potential applications in the development of new drugs and therapeutic agents, particularly in the treatment of various diseases and medical conditions.
Used in Chemical Research:
In the field of chemical research, 4-[6-Chloro-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl]Morpholine serves as a valuable intermediate for the synthesis of complex organic molecules. Its unique structure allows researchers to explore new chemical reactions and develop innovative synthetic pathways, leading to the discovery of novel compounds with potential applications in various industries.
Used in Material Science:
4-[6-Chloro-2-(2-(pyridin-2-yl)ethoxy)pyriMidin-4-yl]Morpholine may also find applications in material science, where trisubstituted pyrimidine compounds can be utilized in the development of advanced materials with specific properties. These materials could be used in various applications, such as sensors, catalysts, or in the creation of new materials with unique electronic, optical, or mechanical properties.

InChI:InChI=1/C15H17ClN4O2/c16-13-11-14(20-6-9-21-10-7-20)19-15(18-13)22-8-4-12-3-1-2-5-17-12/h1-3,5,11H,4,6-10H2

Upstream product

• 103-74-2 2-(2-Hydroxyethyl)pyridine 
• 10397-13-4 4,6-dichloro-2-(morpholine-4-yl)pyrimidine 
• 52127-83-0 4-(2,6-dichloropyrimidin-4-yl)morpholine 

Downstream Products

• 719285-83-3 4-(6-hydrazinyl-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine 
• 541550-67-8 4-{6-chloro-2-[2-(1-oxy-pyridin-2-yl)-ethoxy]-pyrimidin-4-yl}-morpholine 

Relevant articles and documents

Pyrimidine terminal anchor polymerase 2 inhibitor as well as preparation method and application thereof

The invention belongs to the technical field of pharmaceutical chemistry, and particularly relates to a pyrimidine terminal anchor polymerase 2 inhibitor and a preparation method and application thereof. Compared with the prior art, the preparation method

PROCESS FOR PREPARING TRISUBSTITUTED PYRIMIDINE COMPOUNDS

Disclosed herein is a regioselective synthesis of compounds represented by formula (I): or a salt, solvate, clathrate, or prodrug thereof, wherein X, Y, R2, R3, R4, R7, R8, R9, R10/su