54487-71-7

Basic information

• Product Name: 3-benzoyl-1-methyl-indole-2-carboxylic acid
• CAS NO: 54487-71-7
• Molecular Weight: 279.295
• Mol File: 54487-71-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzoyl-1-methyl-indole-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzoyl-1-methyl-indole-2-carboxylic acid(54487-71-7)
• EPA Substance Registry System: 3-benzoyl-1-methyl-indole-2-carboxylic acid(54487-71-7)

Safety Data

• Hazardous Substances Data: 54487-71-7(Hazardous Substances Data)

Upstream product

• 155091-22-8 1-methylindole-2,3-dicarboxylic acid anhydride 
• 2674-04-6 diphenyl cadmium 
• 6296-54-4 ethyl 2,4-dioxo-4-phenylbutyrate 
• 618-40-6 1-Methyl-1-phenylhydrazine 
• 19012-01-2 3-benzoyl-1-methylindole 
• 124-38-9 carbon dioxide 

Downstream Products

• 53704-87-3 5-methyl-1,3-diphenyl-3,5-dihydro-pyridazino[4,5-b]indol-4-one 

Relevant articles and documents

Direct C-2 Carboxylation of 3-Substituted Indoles Using a Combined Br?nsted Base Consisting of LiO-tBu/CsF/18-crown-6

Herein, we report that a combination of LiO-tBu, CsF, and 18-crown-6 can be used to carry out the carboxylation of indole derivatives at the C-2 position under an ambient CO2 atmosphere. Substrates bearing an electrophilic substituent (i.e., cyano, formyl, benzoyl, phenylsulfonyl, phenylsulfinyl, and chloride) at the C-3 position are smoothly converted into their corresponding carboxylated products with high functional group compatibility.