5449-45-6

Basic information

• Product Name: 2-(biphenyl-4-yl)hexanoic acid
• CAS NO: 5449-45-6
• Molecular Formula: C₁₈H₂₀O₂
• Molecular Weight: 268.3502
• Mol File: 5449-45-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 424.4°C at 760 mmHg
• Flash Point: 321.1°C
• Density: 1.077g/cm³
• Vapor Pressure: 5.86E-08mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: 2-(biphenyl-4-yl)hexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(biphenyl-4-yl)hexanoic acid(5449-45-6)
• EPA Substance Registry System: 2-(biphenyl-4-yl)hexanoic acid(5449-45-6)

Safety Data

• Hazardous Substances Data: 5449-45-6(Hazardous Substances Data)

Usage

Derivative of hexanoic acid

2-(biphenyl-4-yl)hexanoic acid is a modified version of hexanoic acid, a six-carbon straight-chain saturated fatty acid.

Contains a biphenyl group

The presence of a biphenyl group (a group consisting of two six-membered carbon rings) in the structure of 2-(biphenyl-4-yl)hexanoic acid.

Industrial and pharmaceutical applications

2-(biphenyl-4-yl)hexanoic acid is used as a building block in the synthesis of other organic compounds and has potential biological and pharmacological activities.

Unique properties

The presence of the biphenyl group gives 2-(biphenyl-4-yl)hexanoic acid unique properties, making it interesting for research and development in the field of organic chemistry.

Upstream product

• 124-38-9 carbon dioxide 
• 2350-89-2 p-vinylbiphenyl 
• 1156-64-5 2,6-dimethyl-4-propyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 5449-21-8 2-([1,1’-biphenyl]-4-yl)-2-oxoacetic acid 
• 92-52-4 biphenyl 
• 854827-33-1 2-biphenyl-4-yl-2-hydroxy-hexanoic acid 
• 6244-53-7 ethyl (4-phenylphenyl)glyoxylate 

Relevant articles and documents

Visible-light-driven external-photocatalyst-free alkylative carboxylation of alkenes with CO2

Herein, we report a novel protocol for visible-light-driven alkylative carboxylation of alkenes with CO2 in the absence of external photocatalyst. Under the irradiation of visible light, a variety of 4-alkyl-1,4-dihydropyridines (alkyl-DHPs) serve as not only alkyl radical precursors but also photoexcited reductants probably with the potential to reduce benzyl radicals. Several styrenes and acrylates are applicable in this reaction to give structurally diverse carboxylic acids in good to excellent yields. These reactions feature mild reaction conditions (1 atm of CO2, room temperature, visible light, photocatalyst- and transition metal-free), good functional group tolerance, easy scalability, as well as high regio-, and chemo-selectivity. Mechanistic investigations provide evidence that alkyl radical, benzyl radical and carbanion might be involved in this reaction, providing a novel strategy for CO2 utilization.[Figure not available: see fulltext.]