54494-06-3

Basic information

• Product Name: 2,2,10,10-Tetramethyl-3,9-dioxa-2,10-disilaundecane
• Synonyms: 2,2,10,10-Tetramethyl-3,9-dioxa-2,10-disilaundecane
• CAS NO: 54494-06-3
• Molecular Formula: C₁₁H₂₈O₂Si₂
• Molecular Weight: 248.5098
• Mol File: 54494-06-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 235.9°Cat760mmHg
• Flash Point: 82.5°C
• Appearance: /
• Density: 0.844g/cm³
• Vapor Pressure: 0.0746mmHg at 25°C
• Refractive Index: 1.416
• CAS DataBase Reference: 2,2,10,10-Tetramethyl-3,9-dioxa-2,10-disilaundecane(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,10,10-Tetramethyl-3,9-dioxa-2,10-disilaundecane(54494-06-3)
• EPA Substance Registry System: 2,2,10,10-Tetramethyl-3,9-dioxa-2,10-disilaundecane(54494-06-3)

Safety Data

• Hazardous Substances Data: 54494-06-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H28O2Si2/c1-14(2,3)12-10-8-7-9-11-13-15(4,5)6/h7-11H2,1-6H3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 111-29-5 1 ,5-pentanediol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 

Downstream Products

• 111-29-5 1 ,5-pentanediol 
• 113849-66-4 C₁₄H₂₄F₃O₂PSi 
• 113849-67-5 C₁₇H₂₀F₆O₂P₂ 

Relevant articles and documents

Efficient and practical protocol for silylation of hydroxyl groups using reusable lithium perchlorate dispread in silica gel under neutral condition

A very efficient and mild procedure for the trimethylsilylation of a wide variety of alcohols, including primary, allylic, benzylic, secondary, hindered secondary, tertiary, and phenols with hexamethyldisilazane on the surface of silica gel dispersed with LiClO4 in room temperature at few minutes in excellent yields under neutral conditions is reported. This procedure also allows the excellent selectivity under LP-SiO2 system for silylation of alcohols in the presence of amine and phenolic hydroxy groups.

Silicon-29 NMR spectra of tert-butyldimethylsilyl and trimethylsilyl derivatives of some non-rigid diols

29Si NMR spectra of trimethylsilyl (TMS) and tert-butyldimethylsilyl (TBDMS) derivatives of selected diols were measured under standardized conditions (i.e., in diluted CDCl3 solutions). Application of the recently reported correlation between the chemical shifts in TMS and TBDMS derivatives revealed considerable and systematic deviations which exceeded experimental errors and error estimates from the correlation. Two possible explanations of the deviations are considered: interaction between the two bulky substituent groups and invalidity of the reported correlation for simple hydroxy derivatives. An independent study of analogous derivatives of monohydroxy compounds has shown that the linear correlation holds but the slope and intercept are significantly different from those reported previously on the basis of a study of amino acid derivatives. The data obtained for the diol derivatives fit the new correlation very well and no indication of an interaction between the bulky TBDMS groups was noticed. However, deviations do occur in branched diol derivatives in which branching reduces accessibility of the oxygen atoms surface to associate with proton donors. The largest deviation was found when intramolecular hydrogen bond was formed.