5452-33-5

Basic information

• Product Name: 3-(benzylsulfanyl)-1,3-diphenylpropan-1-one
• CAS NO: 5452-33-5
• Molecular Formula: C₂₂H₂₀OS
• Molecular Weight: 332.4586
• Mol File: 5452-33-5.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 501.6°C at 760 mmHg
• Flash Point: 283.1°C
• Density: 1.146g/cm³
• Vapor Pressure: 3.41E-10mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: 3-(benzylsulfanyl)-1,3-diphenylpropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(benzylsulfanyl)-1,3-diphenylpropan-1-one(5452-33-5)
• EPA Substance Registry System: 3-(benzylsulfanyl)-1,3-diphenylpropan-1-one(5452-33-5)

Safety Data

• Hazardous Substances Data: 5452-33-5(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 94-41-7 benzalacetophenone 
• 6313-36-6 benzyl thiosulphate 
• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 100-53-8 phenylmethanethiol 
• 93-68-5 3-oxo-N-o-tolylbutanamide 
• 875778-80-6 2-[bis(benzylthio)methylene]-3-oxo-N-o-tolylbutanamide 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 32894-07-8 S-benzyl thioacetimidate hydrochloride 
• 538-28-3 S-benzylisothiourea hydrochloride 
• 536-74-3 phenylacetylene 
• 1817-49-8 1,3-diphenyl-1-propyn-3-ol 

Relevant articles and documents

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Bi(OTf)3 catalyzed synthesis of acyclic β-sulfanyl ketones via a tandem Meyer-Schuster rearrangement/conjugate addition reaction

A new strategy to prepare acyclic β-carbonyl thioethers from propargyl alcohols and sulfur nucleophiles is reported. The investigation of the reaction substrates scope indicated that primary 3-aryl propargyl alcohols and thiols underwent the transformation smoothly. The reaction probably proceeded a Bi(OTf)3-catalyzed tandem Meyer-Schuster rearrangement of 3-aryl propargyl alcohol, followed by a thiol Michael conjugate addition of thiols to in situ generated α, β-unsaturated ketones. The method was 100% atom economic, high-yielding, and easy to handle, making it a valuable method for the construction of β-carbonyl sulfides.

Bifunctional acid-base ionic liquid for the one-pot synthesis of fine chemicals: Thioethers, 2H-chromenes and 2H-quinoline derivatives

A bifunctional organocatalyst with ionic liquid properties and with an optimized distance between the acid and basic sites efficiently activates electron deficient olefins for 1,4 conjugated addition, which can be incorporated in different one-pot transformations for the preparation of cyclic and acyclic compounds of biological and synthetic interest. More specifically, the catalyst can be successfully applied for different carbon-carbon (CC) and carbon-heteroatom (C-N, C-O, C-S) bond forming reactions integrated in a cascade sequence. The activity of the organocatalyst has been compared with that of structurally related monofunctional and bifunctional catalysts. The most attractive features of this procedure are the high atom economy and the use of inexpensive starting materials as well as the use of an environmentally friendly catalyst that can be easily recovered due to its ionic liquid properties.