54541-88-7

Basic information

• Product Name: Phosphorane, triphenyl[3-(trimethylsilyl)-2-propynylidene]-
• Synonyms: triphenyl trimethyl silyl-2-propynyl phosphorane;Phosphorane,triphenyl[3-(trimethylsilyl)-2-propynylidene];(3-Trimethylsilyl-2-propynyl)triphenylphosphorane
• CAS NO: 54541-88-7
• Molecular Formula: C24H25PSi
• Molecular Weight: 372.51500
• Mol File: 54541-88-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Phosphorane, triphenyl[3-(trimethylsilyl)-2-propynylidene]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphorane, triphenyl[3-(trimethylsilyl)-2-propynylidene]-(54541-88-7)
• EPA Substance Registry System: Phosphorane, triphenyl[3-(trimethylsilyl)-2-propynylidene]-(54541-88-7)

Safety Data

• Hazardous Substances Data: 54541-88-7(Hazardous Substances Data)

Upstream product

• 42134-49-6 (3-trimethylsilyl-2-propynyl)triphenylphosphonium bromide 

Relevant articles and documents

Unconventional Fragment Usage Enables a Concise Total Synthesis of (-)-Callyspongiolide

An asymmetric synthesis of (-)-callyspongiolide is described. The route builds the macrolide domain atypically from a disaccharide and a monoterpene without passing through a seco-acid. Chiral iridium catalysis selectively joins fragments. Subsequent degradation of an imbedded butyrolactone via perhemiketal fragmentation affords a stereo- and regio-defined homoallylic alcohol that is engaged directly in a carbonylative macrolactonization. Further elaboration of the polyunsaturated appendage provides the natural product in a particularly direct and flexible manner.