54606-00-7Relevant articles and documents
An efficient synthesis of 2-isoxazolines from α-haloketone oximes and dimethyl sulfonium salts
Zhao, Sen,Wang, Hang,Sun, Shaofa,Guo, Haibing,Chen, Zhiyu,Wang, Jian,Wang, Lu,Liang, Steven,Wang, Gangqiang
supporting information, p. 382 - 385 (2019/01/04)
2-Isoxazolines were synthesized efficiently from a formal [4+1] cycloaddition of nitrosoalkenes and sulfur ylides, which were generated in situ from α-haloketone oximes and dimethyl sulfonium salts. This approach provides a new method to synthesize a rang
3-Aryl-5-vinyl-2-isoxazolines and 3-aryl-5-vinylisoxazoles from aryl nitrile oxides and methyl vinyl ketone lithium enolate: Reaction limits and synthetic utility exploitation
Salomone, Antonio,Scilimati, Antonio,Vitale, Paola
, p. 807 - 816 (2015/03/14)
3-Aryl-5-hydroxy-5-vinyl-2-isoxazolines were synthesized by reacting aryl nitrile oxides with the lithium enolate of methyl vinyl ketone (MVK) at-78 °C. Fair to good yields are obtained in the case of aryl nitrile oxides bearing electron-withdrawing group
2-Isoxazolines with an electron-acceptor substituent at C(5) in reactions with nucleophilic reagents
Koroleva,Bondar,Katok,Chekanov,Chernikhova
, p. 362 - 369 (2008/09/21)
Depending on the substituent at position 5 of the heterocycle, reaction of 2-isoxazolines with K-selectride, molybdenum hexacarbonyl, dimsyl sodium, and butyl lithium gave 1,3-cyclo-decomposition, aromatization of the isoxazoline ring, or reduction of the functional groups in the substituted isoxazolines.