54629-90-2

Basic information

• Product Name: 4-nitro-1-oxido-3-(2-phenylethenyl)pyridine
• Synonyms: 4-nitro-1-oxido-3-(2-phenylethenyl)pyridine
• CAS NO: 54629-90-2
• Molecular Formula: C₁₃H₁₀N₂O₃
• Molecular Weight: 242.23
• Mol File: 54629-90-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 498.9°C at 760 mmHg
• Flash Point: 255.5°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 1.35E-09mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 4-nitro-1-oxido-3-(2-phenylethenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitro-1-oxido-3-(2-phenylethenyl)pyridine(54629-90-2)
• EPA Substance Registry System: 4-nitro-1-oxido-3-(2-phenylethenyl)pyridine(54629-90-2)

Safety Data

• Hazardous Substances Data: 54629-90-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H10N2O3/c16-14-9-8-13(15(17)18)12(10-14)7-6-11-4-2-1-3-5-11/h1-10H

Upstream product

• 1074-98-2 3-methyl-4-nitropyridine N-oxide 
• 100-52-7 benzaldehyde 

Downstream Products

• 37388-07-1 2-phenyl-1H-pyrrolo[3,2-c]pyridine 
• 627511-07-3 4-nitro-3-[(E)-2-phenylethenyl]pyridine 
• 74856-02-3 2,2'-diphenyl-1,1'-pyrrolo<3,2-c>pyridine 
• 627511-08-4 N-{3-[(E)-2-phenylethenyl]pyridin-4-yl}hydroxylamine 

Relevant articles and documents

Synthesis of 2-aryl-1-hydroxyazaindoles and 2-arylazaindoles via oxidation of o-hydroxyaminostyrylpyridines

2-Aryl-1-hydroxyazaindoles (pyrrolopyridin-1-ols) are prepared via an oxidation/cyclization of o-hydroxyaminostyrylpyridines with DDQ. Reduction of the N-OH bond affords the corresponding 2-arylazaindoles (1H-pyrrolopyridines). The scope of the cyclization is explored via (i) the condensation of 4-methyl-3-nitropyridine with various aryl aldehydes to afford 2-aryl substituted 6-azaindoles and, (ii) the synthesis of 2-phenyl-4-, 5- and 7-azaindoles.