5463-22-9

Basic information

• Product Name: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethane-1,2-dione
• CAS NO: 5463-22-9
• Molecular Formula: C₁₆H₁₄O₆
• Molecular Weight: 302.2788
• Mol File: 5463-22-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 555.8°C at 760 mmHg
• Flash Point: 209.2°C
• Density: 1.342g/cm³
• Vapor Pressure: 5.82E-13mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethane-1,2-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethane-1,2-dione(5463-22-9)
• EPA Substance Registry System: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethane-1,2-dione(5463-22-9)

Safety Data

• Hazardous Substances Data: 5463-22-9(Hazardous Substances Data)

Usage

General Description

1,2-bis(4-hydroxy-3-methoxyphenyl)ethane-1,2-dione is a chemical compound that belongs to the class of diarylheptanoids. It is a yellow, crystalline substance that is found in the rhizomes of the plant Curcuma longa, also known as turmeric. 1,2-bis(4-hydroxy-3-methoxyphenyl)ethane-1,2-dione has been studied for its potential antioxidant, anti-inflammatory, and anti-cancer properties. It is also being investigated for its potential therapeutic effects in treating various diseases, including Alzheimer's disease, diabetes, and cardiovascular diseases. The compound has shown promising potential in preclinical studies, but further research is needed to fully understand its biological activities and potential applications in medicine.

Upstream product

• 121-33-5 vanillin 
• 4464-75-9 hydrovanilloin 
• 4464-75-9 1,2-bis-(4-hydroxy-3-methoxyphenyl)ethane-1,2-diol 

Downstream Products

• 109219-48-9 3,4,3',4'-tetrahydroxybenzoin 
• 100622-09-1 3,4,3',4'-tetrahydroxydesoxybenzoin 
• 3842-68-0 4,4'-(ethane-1,2-diyl)dibenzene-1,2-diol 
• 857600-91-0 4,4'-bis-benzyloxy-3,3'-dimethoxy-benzilic acid 
• 854021-39-9 4,4'-bis-benzyloxy-3,3'-dimethoxy-benzophenone 
• 4131-03-7 bis(3,4-dimethoxyphenyl)methanone 
• 7329-69-3 (E)-3,3'-dimethoxy-4,4'-dihydroxystilbene 
• 5963-51-9 1,2-bis(3,4-dimethoxyphenyl)ethane 
• 111329-61-4 3-Allyl-4,4'-dihydroxy-5,3'-dimethoxy-benzil 
• 111329-62-5 4,4'-Dihydroxy-3,3'-dimethoxy-5-propenyl-benzil 
• 6309-15-5 3,3',4,4'-tetrahydroxybenzil 
• 875245-90-2 4-Allyloxy-4'-hydroxy-3,3'-dimethoxy-benzil 
• 7508-46-5 4,4'-Bis-allyloxy-3,3'-dimethoxy-benzil 
• 96970-14-8 4,4'-Bis-benzyloxy-3,3'-dimethoxy-benzil 

Relevant articles and documents

Quinone Dehydrogenation. Oxidation of Benzylic Alcohols with 2,3-Dichloro-5,6-dicyanobenzoquinone

2,3-Dichloro-5,6-dicyanobenzoquinone (DDQ) reacts with primary and secondary aryl-substituted alcohols under mild conditions in dioxane solution to give the corresponding carbonyl compounds in high yields.In contrast to other oxidants, DDQ can be applied advantageously for the oxidation of hydroxyaryl-substituted alcohols.A mechanism involving participation of the phenolic hydroxyl group in the dehydrogenation reaction is discussed.Oxidations of hydroxyaryl-substituted alcohols by DDQ in methanolsolution resulting in the formation of benzoquinones by loss of the hydroxyaryl side chain are interpreted in terms of phenol oxidation.An example of a pyridine-catalyzed Smiles rearrangement of an o-hydroxy-substituted diphenyl ether is reported.