5464-28-8

Basic information

• Product Name: 1,3-Dioxolane-4-methanol
• Synonyms: glycerinformal;glycerolalpha-formal;sericosol-n;METHYLIDENEGLYCEROL;1,3-DIOXOLAN-4-YLMETHANOL;1,3-dioxolane-4-methanol;4-hydroxymethyl-1,3-dioxolan;glycerol 1,2-methylene ether
• CAS NO: 5464-28-8
• Molecular Formula: C₄H₈O₃
• Molecular Weight: 104.1
• EINECS: 225-248-9
• Mol File: 5464-28-8.mol
• Article Data: 28

Chemical Properties

• Melting Point: 192-193°C
• Boiling Point: 192-193 °C(lit.)
• Flash Point: 170 °F
• Appearance: Clear/Liquid
• Density: 1.203 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.13mmHg at 25°C
• Refractive Index: n20/D 1.451(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 14.20±0.10(Predicted)
• CAS DataBase Reference: 1,3-Dioxolane-4-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane-4-methanol(5464-28-8)
• EPA Substance Registry System: 1,3-Dioxolane-4-methanol(5464-28-8)

Safety Data

• Safety Statements: 23-24/25
• WGK Germany: 3
• F: 3
• Hazardous Substances Data: 5464-28-8(Hazardous Substances Data)

Usage

General Description

1,3-Dioxolane-4-methanol, also known as tetrahydro-2H-1,3-dioxol-4-ol, is a chemical compound with the molecular formula C4H8O3. It is a colorless, highly flammable liquid with a faint odor and is soluble in water. This chemical is commonly used as a solvent and as a reagent in organic synthesis. It is also used in the production of pharmaceuticals, agrochemicals, and fragrance ingredients. In addition, 1,3-Dioxolane-4-methanol has been found to have potential applications in the field of energy storage, specifically as a component in the production of lithium-ion batteries. However, it is important to handle and store this compound with caution, as it is a hazardous material that can cause skin and eye irritation and is harmful if ingested or inhaled.

InChI:InChI=1/C4H8O3/c5-1-4-2-6-3-7-4/h4-5H,1-3H2

Upstream product

• 50-00-0 formaldehyd 
• 56-81-5 glycerol 
• 109-87-5 Dimethoxymethane 
• 98238-47-2 4-((benzyloxy)methyl)-1,3-dioxolane 
• 7647-01-0 hydrogenchloride 
• 7664-93-9 sulfuric acid 
• 110-88-3 1,3,5-Trioxan 
• 1404077-71-9 C₉H₁₆O₄ 
• 96-26-4 dihydroxyacetone 
• 107-21-1 ethylene glycol 

Downstream Products

• 22397-01-9 4-benzoyloximethyl-[1,3]dioxolane 
• 91134-12-2 phenyl-carbamic acid-[1,3]dioxolan-4-ylmethyl ester 
• 4362-37-2 4-(chloromethoxy-methyl)-[1,3]dioxolane 
• 130028-42-1 4-([1,3]Dioxolan-4-ylmethoxy)-phthalonitrile 
• 98238-47-2 4-((benzyloxy)methyl)-1,3-dioxolane 
• 130028-45-4 4-(2,4-dinitrophenoxymethyl)-1,3-dioxolane 
• 130028-41-0 4-([1,3]Dioxolan-4-ylmethoxy)-benzonitrile 
• 32061-16-8 1,3-dioxan-5-yl 4-methylbenzene-1-sulfonate 

Relevant articles and documents

Biomass alcoholysis method for petroleum-based plastic POM

The invention discloses a biomass alcoholysis method for petroleum-based plastic POM. According to the method, simple biomass derivative alcohol and the petroleum-based plastic POM are allowed to generate a cyclic acetal product through dehydration condensation under catalytic conditions; low reaction cost and high added value are realized, and only water is byproduced and is easy to separate; and an obtained product has high added value, can be used for preparing organic solvents such as lignin and chromatographic analysis solvents, metal surface treatment agents or medical intermediates and monomers, realizes green, efficient and low-cost recovery, and has a high practical application value.

A bifunctional catalyst based on Nb and v oxides over alumina: Oxidative cleavage of crude glycerol to green formic acid

A bimetallic vanadium and niobium oxide catalyst using alumina as support was developed for the conversion of crude glycerol from biodiesel production into formic acid. The high dispersion of the active oxide phase combined with the presence of acid and redox active centers resulted in a high glycerol conversion (>90% for 25 h) with a good selectivity for formic acid (～55%). This process is the first example of a heterogeneous liquid-phase process for the conversion of crude glycerol to formic acid, which is an important chemical intermediate currently derived from petroleum feedstock.

Glycerolformal industrial production method

The invention discloses a glycerolformal industrial production method. The glycerolformal industrial production method achieves synthesis of glycerolformal by taking SO42-/ZrO2-CNTS (carbon nanotubes)super acids as catalysts. The glycerolformal industrial production method is low in reaction temperature, high in activity of catalysts, free from introduction of new water-carrying agent and short in reaction time; the products achieve a yield of higher than 92% and a high proportional ratio of hexatomic ring products.