5464-77-7 Usage
Description
N,N-Dibenzylformamide, with the CAS number 5464-77-7, is a white solid compound that is primarily utilized in the field of organic synthesis. It is known for its unique chemical properties that make it a valuable component in various chemical reactions and processes.
Uses
Used in Organic Synthesis:
N,N-Dibenzylformamide is used as a synthetic intermediate for the production of various organic compounds. Its application in this field is due to its ability to participate in a range of chemical reactions, such as condensation, substitution, and rearrangement reactions, which are essential for the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N-Dibenzylformamide is used as a building block for the development of new drugs. Its unique chemical structure allows it to be modified and functionalized to create novel drug candidates with potential therapeutic applications.
Used in Chemical Research:
N,N-Dibenzylformamide is also employed in chemical research as a model compound to study various reaction mechanisms and to develop new synthetic methodologies. Its reactivity and structural features make it an ideal candidate for exploring new chemical transformations and understanding the underlying principles of organic chemistry.
Used in Material Science:
In the field of material science, N,N-Dibenzylformamide can be used as a component in the development of new materials with specific properties. Its incorporation into polymers or other materials can lead to the creation of materials with enhanced characteristics, such as improved stability, reactivity, or selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 5464-77-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,6 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5464-77:
(6*5)+(5*4)+(4*6)+(3*4)+(2*7)+(1*7)=107
107 % 10 = 7
So 5464-77-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H15NO/c17-13-16(11-14-7-3-1-4-8-14)12-15-9-5-2-6-10-15/h1-10,13H,11-12H2
5464-77-7Relevant articles and documents
Conversion of (1-heterodiene)tricarbonyliron(0) complexes into (2-aminohomodiene)tricarbonyliron(0) complexes
Ackland, Mark J.,Danks, Timothy N.,Howells, Mark E.
, p. 691 - 694 (1996)
Treatment of (1-azadiene)tricarbonyliron(0) complex 1 with lithiated amines leads to attack at a metal carbonyl and the formation of formamides, whereas complexes 2 and 3 undergo deprotonation of the methyl group at C-2 followed by a rearrangement to form (2-aminohomodiene)tricarbonyliron(0) complexes 8 or 10 in good yield.
Borane-Trimethylamine Complex as a Reducing Agent for Selective Methylation and Formylation of Amines with CO2
Zhang, Yanmeng,Zhang, He,Gao, Ke
supporting information, p. 8282 - 8286 (2021/10/25)
We report herein that a borane-trimethylamine complex worked as an efficient reducing agent for the selective methylation and formylation of amines with 1 atm CO2 under metal-free conditions. 6-Amino-2-picoline serves as a highly efficient catalyst for the methylation of various secondary amines, whereas in its absence, the formylation of primary and secondary amines was achieved in high yield with high chemoselectivity. Mechanistic studies suggest that the 6-amino-2-picoline-borane catalytic system operates like an intramolecular frustrated Lewis pair to activate CO2.
Recyclable Oxofluorovanadate-Catalyzed Formylation of Amines by Reductive Functionalization of CO2 with Hydrosilanes
Wu, Shanxuan,Huang, Zijun,Jiang, Xiaolin,Yan, Fachao,Li, Yuehui,Du, Chen-Xia
, p. 1763 - 1766 (2021/03/01)
An efficient method has been developed for the reductive amination of CO2 by using readily available and recyclable oxofluorovanadates as catalysts. Various amines are transformed into the desired N-formylated products in moderate to excellent yields at room temperature in the presence of phenylsilane. Mechanistic studies based on in situ infrared spectroscopy suggest a reaction pathway initiated through F?Si interactions. The activated phenylsilane allows for CO2 insertion to produce phenylsilyl formate, which undergoes attack by the amine to generate the target product.
