547-44-4 Usage
Description
SULFANILYLUREA, also known as Sulfa, is a synthetic compound belonging to the class of sulfonamide antibiotics. It is a white solid with potent antibacterial properties, making it a widely used pharmaceutical agent. Its chemical structure allows it to inhibit bacterial growth by interfering with the synthesis of folic acid, which is essential for bacterial replication.
Uses
Used in Pharmaceutical Industry:
SULFANILYLUREA is used as an antibiotic for treating various bacterial infections. It is particularly effective against gram-positive bacteria and some gram-negative bacteria, making it a valuable component in the fight against infections.
Used in Veterinary Medicine:
In the veterinary field, SULFANILYLUREA is used as an antimicrobial agent to prevent and treat bacterial infections in animals. Its broad-spectrum activity ensures the effective control of various bacterial pathogens, contributing to the overall health and well-being of animals.
Used in Agricultural Industry:
SULFANILYLUREA is also utilized in the agricultural sector as an antimicrobial agent to protect crops from bacterial diseases. Its application helps in reducing crop losses and improving overall yield, thereby contributing to food security.
Used in Research and Development:
As a labeled analogue, Sulfacarbamide-d4 (S688945) serves as a valuable tool in research and development for studying the mechanisms of action, metabolism, and pharmacokinetics of SULFANILYLUREA. This helps in the development of new drugs and understanding the interactions of SULFANILYLUREA with various biological systems.
World Health Organization (WHO)
Sulfacarbamide, a sulfonamide anti-infective agent, was
introduced in the 1940's for the treatment of bacterial infections. The importance of
sulfonamides has subsequently decreased as a result of increasing bacterial
resistance and their replacement by antibiotics which are generally more active
and less toxic. The Sulfacarbamide are known to cause serious adverse effects
such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema
multiforma and dangerous adverse reactions affecting blood formation such as
agranulocytosis and haemolytic or aplastic anaemia. Sulfacarbamide still remains
available in at least one country for the treatment of urinary infections.
Check Digit Verification of cas no
The CAS Registry Mumber 547-44-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 7 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 547-44:
(5*5)+(4*4)+(3*7)+(2*4)+(1*4)=74
74 % 10 = 4
So 547-44-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H9N3O3S/c8-5-1-3-6(4-2-5)14(12,13)10-7(9)11/h1-4H,8H2,(H3,9,10,11)
547-44-4Relevant articles and documents
Insight into sulfamethoxazole degradation, mechanism, and pathways by AgBr-BaMoO4 composite photocatalyst
Ray, Schindra Kumar,Dhakal, Dipesh,Lee, Soo Wohn
, p. 686 - 695 (2018/07/14)
A composite photocatalyst, AgBr-BaMoO4 was fabricated by two step method; microwave hydrothermal and precipitation-deposition. The as prepared photocatalyst samples were characterized by various techniques. The facet coupling was seen between the (204) plane of BaMoO4 and (200)/(222) planes of AgBr on the basis of XRD/HRTEM analysis. The pharmaceutical pollutant, sulfamethoxazole was adopted to investigate the photocatalytic performances of samples under UV–vis irradiation. The AgBr-BaMoO4 composite degraded the aqueous sulfamethoxazole drug in UV–vis light about 64% within 75 min, which was attributed to efficient separation of photogenerated electron–hole pairs across the interface between Ag/AgBr and BaMoO4. The multi-electron induced oxygen reduced reaction (ORR) was observed. The radical trapping experiment indicates that OH? has major role for sulfamethoxazole degradation. The four successive photodegradation of sulfamethoxazole in UV–vis light indicates the stability of composite photocatalyst. Furthermore, the three different degradation pathways were designed on the basis of retention time and molecular masses of 18 degraded organic fragments that was confirmed by high-performance liquid chromatography photodiode array (HPLC-PDA) and high resolution-quadruple time of flight electrospray ionization mass spectroscopy (HR-QTOF ESI/MS) techniques. The total organic carbon (TOC) analysis suggested the mineralization of SMZ by composite photocatalyst. This study not only demonstrates the enhancement of photocatalytic performance of wide band gap semiconductor by making composite with narrow band gap semiconductor but also detail degradation pathways and mechanisms of sulfamethoxazole.