54705-16-7

Basic information

• Product Name: Benzamide, 2-(methylthio)-
• Synonyms: 2-methylsulfanyl-benzamide;2-methylsulfanyl-benzoic acid amide;2-Methylmercapto-benzamid;2-Methylmercapto-benzoesaeure-amid;2-(methylthio)benzamide;Benzamide,2-(methylthio);S-Methyl-thiosalicylsaeure-amid;2-Methylthiobenzamid
• CAS NO: 54705-16-7
• Molecular Formula: C8H9NOS
• Molecular Weight: 167.232
• Mol File: 54705-16-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 149-150 °C
• Boiling Point: 316.7±25.0 °C(Predicted)
• Density: 1.21±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzamide, 2-(methylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-(methylthio)-(54705-16-7)
• EPA Substance Registry System: Benzamide, 2-(methylthio)-(54705-16-7)

Safety Data

• Hazardous Substances Data: 54705-16-7(Hazardous Substances Data)

Upstream product

• 1442-03-1 2-methylsulfanyl-benzoyl chloride 
• 249764-80-5 C₁₇H₁₉NOS 
• 82573-53-3 N-(1-methyl-1-phenylethyl)benzamide 
• 98-88-4 benzoyl chloride 
• 10283-95-1 N-allylbenzamide 
• 3724-10-5 2-(methylthio)benzoic acid 
• 6609-54-7 2-cyanothioanisole 
• 3704-28-7 methyl 2-(methylthio)benzoate 

Downstream Products

• 54705-22-5 2-methanesulfinyl-benzamide 
• 118362-22-4 C₁₅H₁₆N₂O₃S₂ 
• 1186372-29-1 1-(2-methylthiobenzoyl)-3-(9H-fluoren-9-yl)-urea 
• 2634-33-5 1,2-benzisothiazolin-3-one 
• 37527-97-2 (2-Methanesulfinyl-benzyl)-carbamic acid methyl ester 
• 37527-98-3 (2-Methylsulfanyl-benzyl)-carbamic acid methyl ester 
• 57076-00-3 2-(methylsulfonyl)benzimidamide 
• 57553-04-5 3-cyclohexyloxycarbonylimino-1-methyl-3H-1λ⁴-benzo[d]isothiazole 1-oxide 
• 55981-04-9 3-(2-hydroxy-benzoylimino)-1-methyl-3H-1λ⁴-benzo[d]isothiazole 1-oxide 
• 55981-01-6 1-methyl-3-phenoxycarbonylimino-3H-1λ⁴-benzo[d]isothiazole 1-oxide 
• 58099-01-7 1-methyl-3-phenylcarbamoylimino-3H-1λ⁴-benzo[d]isothiazole 1-oxide 
• 58099-02-8 3-(allyl-thiocarbamoylimino)-1-methyl-3H-1λ⁴-benzo[d]isothiazole 1-oxide 
• 58099-00-6 3-cyanoimino-1-methyl-3H-1λ⁴-benzo[d]isothiazole 1-oxide 
• 52369-06-9 2-methylsulfanyl-thiobenzoic acid amide 

Relevant articles and documents

Synthetic method 1-2 - benzisothiazol -3 -one compound (by machine translation)

The invention discloses a synthetic method of 1-2 - benzisothiazol -3 -one compound, and belongs to the field of chemical synthesis. 2 - 1-benzisothiazol 2 -one compounds are synthesized through acid chlorination, amidation and cyclization reaction by using the sulfenyl-substituted benzoic acid extracted from BIT process -3 - waste water as a starting raw material. The method disclosed by the invention has the advantages of mild reaction conditions, simple and convenient operation, strong practicability, less waste water, high product purity and the like, and is suitable for large-scale industrial production. The technical scheme provided by the invention is resource utilization and preparation 1 of wastewater extract produced in BIT production, and a feasible method is provided for the 2 -benzisothiazol -3 -one compound. (by machine translation)

Benzisothiazol-3-ones through a Metal-Free Intramolecular N–S Bond Formation

The highly efficient synthesis of benzoisothiazol-3-ones from thiobenzamides has been described with good functional group compatibility and excellent yields. This work represents the first example of selectfluor-promoted N–S bond formation processes. This method provides a facile approach to access various important bioactive benzoisothiazol-3-ones.

N-cumyl benzamide, sulfonamide, and aryl O-carbamate directed metalation groups. Mild hydrolytic lability for facile manipulation of directed ortho metalation derived aromatics

(Matrix Presented) N-Cumyl benzamide (2), sulfonamide (8), and O-carbamate (11) compounds undergo directed ortho metalation under standard conditions to give, after quench with a variety of electrophiles, the substituted products 3, 9, and 12, respectively. Regiospecific and convenient approaches to phthalimides (7), 1,2-benzisothiazole 1,1-dioxides (10b), and ortho-substituted phenols (13a) and salicylamides (13b) are thereby established The mild deprotection protocol for these new cumyl directed metalation groups (DMGs) suggests that they will supersede previous corresponding groups for synthetic anionic aromatic chemistry.