54756-24-0

Basic information

• Product Name: 2-benzoyl-2-hydroxy-1-benzofuran-3(2H)-one
• Synonyms: 2-Benzoyl-2-hydroxy-1-benzofuran-3(2H)-one; 3(2H)-benzofuranone, 2-benzoyl-2-hydroxy-
• CAS NO: 54756-24-0
• Molecular Formula: C₁₅H₁₀O₄
• Molecular Weight: 254.2375
• Mol File: 54756-24-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 465.9°C at 760 mmHg
• Flash Point: 181.5°C
• Density: 1.424g/cm³
• Vapor Pressure: 1.77E-09mmHg at 25°C
• Refractive Index: 1.67
• CAS DataBase Reference: 2-benzoyl-2-hydroxy-1-benzofuran-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzoyl-2-hydroxy-1-benzofuran-3(2H)-one(54756-24-0)
• EPA Substance Registry System: 2-benzoyl-2-hydroxy-1-benzofuran-3(2H)-one(54756-24-0)

Safety Data

• Hazardous Substances Data: 54756-24-0(Hazardous Substances Data)

Upstream product

• 577-85-5 3-hydroxyflavone 

Relevant articles and documents

Flavonoid epoxides. Part 20. Some unusual reactions of dimethyldioxirane (DMD) with flavonoid compounds

Dimethyldioxirane (DMD), generally as a solution in acetone, has proved itself to be an excellent epoxidising agent. It was observed that either the 2'-hydroxychalcone epoxide or the tans-2,3-dihydroflavonol could be obtained depending on the pH of the reaction mixture and the type of β-arene ring present in the substrate. Using this methodology trans-2,3-dihydroflavonols can be synthesised in far better yields than by the most commonly used method for their synthesis, that of the Algar-Flynn-Oyamada reaction. Treatment of both flavonol 14 and the novel isoaurone 21 with DMD gave unusual products instead of the expected epoxides, but nonetheless, an epoxide was assumed to have formed during the reaction.