5485-91-6

Basic information

• Product Name: Benzoyl chloride, 2-(acetyloxy)-5-bromo-
• CAS NO: 5485-91-6
• Molecular Formula: C9H6BrClO3
• Molecular Weight: 277.502
• Mol File: 5485-91-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 2-(acetyloxy)-5-bromo-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 2-(acetyloxy)-5-bromo-(5485-91-6)
• EPA Substance Registry System: Benzoyl chloride, 2-(acetyloxy)-5-bromo-(5485-91-6)

Safety Data

• Hazardous Substances Data: 5485-91-6(Hazardous Substances Data)

Upstream product

• 89-55-4 5-bromosalicyclic acid 
• 1503-53-3 2-acetyloxy-5-bromobenzoic acid 

Downstream Products

• 55981-17-4 2-acetoxy-5-bromo-N-(5-nitro-thiazol-2-yl)-benzamide 
• 1237514-87-2 tert-butyl 2-(2-acetoxy-5-bromobenzamido)-4-phenylbenzoate 
• 1237514-96-3 methyl 2-(2-acetoxy-5-bromobenzamido)-4-phenylbenzoate 
• 1237519-45-7 C₃₂H₂₉NO₅ 
• 1237519-42-4 C₂₄H₂₂BrNO₄ 
• 1237515-10-4 2-(5-(6-aminopyridin-2-yl)-2-hydroxybenzamido)-4-phenylbenzoic acid 
• 1237519-49-1 tert-butyl 2-(5-(6-aminopyridin-2-yl)-2-hydroxybenzamido)-4-phenylbenzoate 
• 1237515-09-1 tert-butyl 2-(2-acetoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamido)-4-phenylbenzoate 
• 1237515-05-7 2-(5-(furan-2-yl)-2-hydroxybenzamido)-4-phenylbenzoic acid 
• 1237519-47-9 methyl 2-(2-acetoxy-5-(furan-2-yl)benzamido)-4-phenylbenzoate 
• 1237515-04-6 2-(2-hydroxy-5-phenylbenzamido)-4-phenylbenzoic acid 
• 1237519-46-8 tert-butyl 2-(2-hydroxy-5-phenylbenzamido)-4-phenylbenzoate 
• 1237515-00-2 2-(5-bromo-2-hydroxybenzamido)-4-phenylbenzoic acid 
• 133001-95-3 2,2-dimethyl-6-bromo-3,4-dihydro-2H-1,3-benzoxazin-4-one 

Relevant articles and documents

Synthesis and antioxidant activities of berberine 9-: O -benzoic acid derivatives

Although berberine (BBR) shows antioxidant activity, its activity is limited. We synthesized 9-O-benzoic acid berberine derivatives, and their antioxidant activities were screened via ABTS, DPPH, HOSC and FRAP assays. The para-position was modified with halogen elements on the benzoic acid ring, which led to an enhanced antioxidant activity and the substituent on the ortho-position was found to be better than the meta-position. Compounds 8p, 8c, 8d, 8i, 8j, 8l, and especially 8p showed significantly higher antioxidant activities, which could be attributed to the electronic donating groups. All the berberine derivatives possessed proper lipophilicities. In conclusion, compound 8p is a promising antioxidant candidate with remarkable elevated antioxidant activity and moderate lipophilicity.

N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF

An N-acyl anthranilic acid derivative represented by general formula (1) or a salt thereof is useful for prevention or treatment of diseases associated with excessive production of collagen. (In the formula, R1 represents a carboxyl group or the like; R2 represents a hydrogen atom or the like; R3 represents an optionally substituted aryl group or the like; X1 represents a carbonyl group; X2 represents a bonding hand; X3 represents a bonding hand; X4 represents a bonding hand or the like; and A represents an optionally substituted phenyl group or the like.)

ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION

This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, and their use in treating human or animal disorders. The compounds of the invention are useful as antagonists, or more preferably, partial antagonist of factor IX and thus, may be used to inhibit the intrinsic pathway of blood coagulation. The compounds are useful in a variety of applications including the management, treatment and/or control of diseases caused in part by the intrinsic clotting pathway utilizing factor IX. Such diseases or disease states include stroke, myocardial infarction, aneurysm surgery, and deep vein thrombosis associated with surgical procedures, long periods of confinement, and acquired or inherited pro-coagulant states.