548756-58-7

Basic information

• Product Name: tert-butyl 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-2-methylenenpropanoate
• Synonyms: tert-butyl 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-2-methylenenpropanoate
• CAS NO: 548756-58-7
• Molecular Weight: 329.191
• Mol File: 548756-58-7.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-2-methylenenpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-2-methylenenpropanoate(548756-58-7)
• EPA Substance Registry System: tert-butyl 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-2-methylenenpropanoate(548756-58-7)

Safety Data

• Hazardous Substances Data: 548756-58-7(Hazardous Substances Data)

Upstream product

• 548756-59-8 tert-butyl 3-(3,5-dibromo-2-hydroxyphenyl)-3-hydroxy-2-methylenenpropanoate 
• 548756-57-6 tert-butyl 3-(3-ethoxy-2-hydroxyphenyl)-3-hydroxy-2-methylenenpropanoate 
• 548756-56-5 tert-butyl 3-hydroxy-3-(2-hydroxy-3-methoxyphenyl)-2-methylenenpropanoate 
• 1663-39-4 tert-Butyl acrylate 
• 1761-61-1 5-bromosalicyclaldehyde 

Downstream Products

• 548756-55-4 tert-butyl 3-hydroxy-3-(2-hydroxyphenyl)-2-methylenenpropanoate 
• 548756-56-5 tert-butyl 3-hydroxy-3-(2-hydroxy-3-methoxyphenyl)-2-methylenenpropanoate 
• 548756-57-6 tert-butyl 3-(3-ethoxy-2-hydroxyphenyl)-3-hydroxy-2-methylenenpropanoate 
• 515160-01-7 6-bromo-3-(chloromethyl)coumarin 
• 380607-15-8 6-bromo-2H-chromene-3-carboxylic acid 
• 1481639-85-3 2-benzylthio-N-[(6-bromo-2-oxo-2H-1-benzopyran-3-yl)methyl]ethylamine 
• 1481639-86-4 2-benzylthio-N,N-bis[(6-bromo-2-oxo-2H-1-benzopyran-3-yl)methyl]ethylamine 
• 1663-39-4 tert-Butyl acrylate 
• 1761-61-1 5-bromosalicyclaldehyde 

Relevant articles and documents

Does the DABCO-catalysed reaction of 2-hydroxybenzaldehydes with methyl acrylate follow a Baylis-Hillman pathway?

Evidence is presented which supports the intermediacy of dipolar Baylis-Hillman-type adducts in the synthesis of coumarin and chromene derivatives from the reaction of 2-hydroxybenzaldehydes with methyl acrylate in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO).

Application of Baylis-Hillman methodology in the direct construction of chromone derivatives

Pyridinium chlorochromate oxidation of Baylis-Hillman-derived tert-butyl 2H-chromene-3-carboxylates affords chromone-3-carboxylate esters, providing the first application of Baylis-Hillman methodology in a direct and convenient three-step synthesis of chr

Synthesis and evaluation of 3-hydroxy-3-phenylpropanoate ester-AZT conjugates as potential dual-action HIV-1 Integrase and Reverse Transcriptase inhibitors

Novel 3-hydroxy-3-phenylpropanoate ester-azidothymidine (AZT) conjugates have been prepared using Baylis-Hillman methodology, and their potential as dual-action HIV-1 Integrase and Reverse Transcriptase inhibitors has been explored using enzyme inhibition