548763-91-3Relevant articles and documents
Synthesis and structure-activity relationship for a novel class of potent and selective carbamate-based inhibitors of hormone selective lipase with acute in vivo antilipolytic effects
Ebdrup, S?ren,Refsgaard, Hanne Hoffmann Fr?lund,Fledelius, Christian,Jacobsen, Poul
, p. 5449 - 5456 (2007)
Hormone-sensitive lipase (HSL) is an intracellular enzyme that has a central role in the regulation of fatty acid metabolism. The enzyme, therefore, is a potentially interesting pharmacological target for the treatment of insulin resistance and dyslipidem