5490-27-7

Basic information

• Product Name: Dihydrostreptomycin sulfate
• Synonyms: D-Streptamine, O-2-deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1?2)-O-5-deoxy-3-C-(hydroxymethyl)-.alpha.-L-lyxofuranosyl-(1?4)-N,N-bis(aminoiminomethyl)-, sulfate (2:3) (salt);dihydrostreptomycin solution;DIHYDROSTREPTOMYCINSULPHATE(INJ.);DIHYDROSTREPTOMYCINSULPHATE(ORAL);Dihydrostreptomycin sulfate;Prestwick_173;Dihydrostreptomycin Sulfate (200 mg);Double-Mycin
• CAS NO: 5490-27-7
• Molecular Formula: 2C₂₁H₄₁N₇O₁₂*3H₂O₄S
• Molecular Weight: 1451.38
• EINECS: 226-823-7
• Product Categories: PHARMACEUTICALS;A - KAntibiotics;AminoglycosidesAntibiotics;Antibiotics A-FAntibiotics;Antibiotics by Application;AntimycobacterialAntibiotics;Chemical Structure Class;Genetic Marker SelectionAntibiotics;Interferes with Protein SynthesisMore...Close...;Mechanism of Action;Antibacterial;Antibiotics A to;Spectrum of Activity;Agro-Products;Amines;Carbohydrates & Derivatives;Intermediates & Fine Chemicals
• Mol File: 5490-27-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 954.5 °C at 760 mmHg
• Flash Point: 531.1 °C
• Appearance: white to light yellow/crystalline
• Vapor Pressure: 0mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: H2O: 50 mg/mL, clear, faintly yellow
• Water Solubility: Soluble in water
• Merck: 13,3201
• BRN: 3894221
• CAS DataBase Reference: Dihydrostreptomycin sulfate(CAS DataBase Reference)
• NIST Chemistry Reference: Dihydrostreptomycin sulfate(5490-27-7)
• EPA Substance Registry System: Dihydrostreptomycin sulfate(5490-27-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: WK2236000
• TSCA: Yes
• Hazardous Substances Data: 5490-27-7(Hazardous Substances Data)

Usage

Description

Dihydrostreptomycin sulfate is a derivative of Streptomycin, an antibiotic with potent antimicrobial properties. It is a white solid substance that has been utilized in various applications due to its effectiveness in combating infections and controlling pests.

Uses

Used in Veterinary Medicine:
Dihydrostreptomycin sulfate is used as an antibiotic for treating bovine infections. Its antimicrobial activity helps in controlling and eliminating bacterial infections in cattle, ensuring their health and productivity.
Used in Crop Protection:
As an effective antibiotic, Dihydrostreptomycin sulfate is also utilized in the agricultural industry to control pests found in crops. By targeting and eliminating harmful bacteria and microorganisms, it contributes to the protection and growth of crops, thereby increasing yield and ensuring food security.
Used in Cochlear Amplification:
In the field of biology and auditory research, Dihydrostreptomycin sulfate has been employed as an electrode for a cochlear amplifier in the hair-cell bundle of lizards. This application aids in the study of auditory mechanisms and the functioning of the cochlea in reptiles, providing valuable insights into the evolution of hearing and the development of new technologies for hearing aids and cochlear implants.

Therapeutic Function

Antibiotic

Purification Methods

It crystallises from H2O, MeOH, n-BuOH or methyl ethyl ketone. The crystals are not hygroscopic like the amorphous powder; however, both forms are soluble in H2O but the amorphous solid is about 10 times more soluble than the crystals. The free base also crystallises from H2O/Me2CO and has [] D -92o (aqueous solution pH 7.0). [Solomons & Regina Science 109 515 1949, Wolf et al. Science 109 515 1949, McGilveray & Rinehart J Am Chem Soc 87 4003 1956]. [Beilstein 18 III/IV 7538.]

InChI:InChI=1/2C21H41N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*5-18,26,29-36H,3-4H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,21+;;;/m00.../s1