54934-41-7

Basic information

• Product Name: Bicyclo[2.2.1]heptan-2-ol, 1-(mercaptomethyl)-7,7-dimethyl-, (1R,2S,4S)-rel-
• CAS NO: 54934-41-7
• Molecular Formula: C10H18OS
• Molecular Weight: 186.318
• Mol File: 54934-41-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Bicyclo[2.2.1]heptan-2-ol, 1-(mercaptomethyl)-7,7-dimethyl-, (1R,2S,4S)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: Bicyclo[2.2.1]heptan-2-ol, 1-(mercaptomethyl)-7,7-dimethyl-, (1R,2S,4S)-rel-(54934-41-7)
• EPA Substance Registry System: Bicyclo[2.2.1]heptan-2-ol, 1-(mercaptomethyl)-7,7-dimethyl-, (1R,2S,4S)-rel-(54934-41-7)

Safety Data

• Hazardous Substances Data: 54934-41-7(Hazardous Substances Data)

Upstream product

• 4552-50-5 camphorsulfonyl chloride 

Downstream Products

• 1439-07-2 (R,R)-trans-stilbene epoxide 

Relevant articles and documents

Process for the preparation of an oxirane, aziridine or cyclopropane

A process for the preparation of an oxirane, aziridine or cyclopropane of formula (I), wherein X is oxygen, NR4or CHR5; R1is hydrogen, alkyl, aryl, heteroaromatic, heterocyclic or cycloalkyl; R2is hydrogen, alkyl, aryl, heteroaromatic, CO2R8, CHR14NHR13, heterocyclic or cycloalkyl; or R1and R2join together to form a cycloalkyl ring; R3and R10are, independently, hydrogen, alkyl, aryl, heteroaromatic, CO2R8, R83Sn, CONR8R9, trialkylsilyl or triarylsilyl; R4is an electron withdrawing group; R5is alkyl, cycloalkyl, aryl, heteroaromatic, SO2R8, SO3R8, COR8, CO2R8, CONR8R9, PO(R8)2, PO(OR8)2or CN; R8and R9are independently alkyl or aryl; and R13and R14are independently hydrogen, alkyl or aryl is provided. The process comprises degrading a compound of formula (II), (IIa), (IIb) or (IIc): wherein R3and R10are as defined above; Y is a cation; depending on the nature of Y, r is 1 or 2; and L is a suitable leaving group, to form a diazo compound. The diazo compound is reacted with a suitable transition metal catalyst, and the product thereof reacted with a sulphide of formula SR6R7, wherein R6and R7are independently alkyl, aryl or heteroaromatic, or R6and R7join together to form an optionally substituted ring which optionally includes an additional heteroatom. This product is then reacted with an aldehyde, ketone, imine or alkene.