54950-12-8 Usage
Structure
Pyrimidine derivative with a pyridine ring attached to the 6th position of the pyrimidine ring
Functional Groups
Amino group ( \textNH2 ) at the 2nd position of the pyridine ring
Carbonyl group ( \textC=O ) at the 4th position of the pyrimidine ring
Common Use
Building block for synthesizing various drug molecules
Biological Activities
Studied for potential biological activities in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 54950-12-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,9,5 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 54950-12:
(7*5)+(6*4)+(5*9)+(4*5)+(3*0)+(2*1)+(1*2)=128
128 % 10 = 8
So 54950-12-8 is a valid CAS Registry Number.
54950-12-8Relevant articles and documents
HETEROARYLOXY-SUBSTITUTED PHENYLAMINOPYRIMIDINES AS RHO-KINASE INHIBITORS
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, (2010/02/06)
The invention relates to heteroaryloxy-substituted phenylaminopyrimidines, to methods for the production thereof, and to the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular diseases. The inventive compounds inhibit Rho-kinase.
RHO-KINASE INHIBITORS
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Page/Page column 11, (2008/06/13)
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PYRIMIDONE DERIVATIVES
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Page 56, (2008/06/13)
A pyrimidone derivative represented by the formula (I) or a salts thereof: wherein R1 represents an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, an aryl group and the like; R2 represents a hydrogen atom, hydro
