54962-75-3 Usage
Description
3-Amino-5-bromobenzotrifluoride is an organic compound characterized by its white solid appearance. It is a derivative of benzotrifluoride with a bromine atom at the 5th position and an amino group at the 3rd position. 3-Amino-5-bromobenzotrifluoride is known for its unique chemical properties, which make it a valuable intermediate in the synthesis of various organic compounds.
Uses
Used in Pharmaceutical Industry:
3-Amino-5-bromobenzotrifluoride is used as a synthetic intermediate for the production of various pharmaceutical compounds. Its unique structure allows for the creation of a wide range of molecules with potential therapeutic applications.
Used in Chemical Synthesis:
3-Amino-5-bromobenzotrifluoride is used as a key building block in the synthesis of complex organic molecules. Its reactivity and functional groups make it a versatile compound for use in various chemical reactions, leading to the formation of a diverse array of products.
Used in the Synthesis of 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline:
Specifically, 3-Amino-5-bromobenzotrifluoride may be used in the synthesis of 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline, a compound with potential applications in various fields, such as pharmaceuticals, materials science, and chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 54962-75-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,9,6 and 2 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 54962-75:
(7*5)+(6*4)+(5*9)+(4*6)+(3*2)+(2*7)+(1*5)=153
153 % 10 = 3
So 54962-75-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H10F26O4/c21-9(22,11(25,26)13(29,30)15(33,34)17(37,38)19(41,42)43)3-5-49-7(47)1-2-8(48)50-6-4-10(23,24)12(27,28)14(31,32)16(35,36)18(39,40)20(44,45)46/h1-2H,3-6H2/b2-1+
54962-75-3Relevant articles and documents
Nilotinib hydrochloride bulk drug impurity and preparation method thereof
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Paragraph 0039; 0048-0050; 0055-0057; 0060-0062; 0065-0067, (2021/05/12)
The invention provides a preparation method of a nilotinib hydrochloride bulk drug impurity. The preparation method comprises the following steps: S1) reducing a compound as shown in a formula (II) to obtain a compound as shown in a formula (III); and S2) subjecting the compound as shown in the formula (III) to reacting with imidazole to obtain the nilotinib hydrochloride bulk drug impurity as shown in the formula (I). The formulas are as defined in the specification, and X in the formulas is halogen. Compared with the prior art, the preparation method of the impurity in the initial raw material of nilotinib hydrochloride provided by the invention has the advantages that raw materials are easy to obtain, a process route is relatively short, precious metals such as palladium can be prevented from being used for a reaction, quinoline compounds are not used, and residues of the quinoline compounds are avoided; and the method can be used for process development, production, quality standard establishment and quality control links of nilotinib, and provides technical support for the medication safety of the monohydrate nilotinib hydrochloride.
