550-37-8 Usage
Description
2-PENTANOYLBENZOIC ACID is an organic compound with the molecular structure featuring a pentanoyl chain attached to a benzoic acid moiety. It is characterized by its chemical properties and potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
2-PENTANOYLBENZOIC ACID is used as an intermediate in the synthesis of various pharmaceutical compounds, such as N-butylphthalide, which is known to alleviate blood-brain barrier impairment in rats exposed to carbon monoxide. Its unique structure allows it to be a versatile building block for the development of new drugs and therapeutic agents.
Used in Chemical Synthesis:
2-PENTANOYLBENZOIC ACID is used as a key component in the synthesis of various organic compounds, including those with potential applications in the fields of materials science, agrochemicals, and specialty chemicals. Its reactivity and functional groups make it a valuable precursor for the creation of novel molecules with specific properties and functions.
Used in Research and Development:
2-PENTANOYLBENZOIC ACID serves as a valuable research tool for scientists and researchers working on the development of new chemical processes, materials, and pharmaceuticals. Its unique structure and properties can provide insights into the behavior of similar compounds and contribute to the advancement of scientific knowledge in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 550-37-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,5 and 0 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 550-37:
(5*5)+(4*5)+(3*0)+(2*3)+(1*7)=58
58 % 10 = 8
So 550-37-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H14O3/c1-2-3-8-11(13)9-6-4-5-7-10(9)12(14)15/h4-7H,2-3,8H2,1H3,(H,14,15)
550-37-8Relevant articles and documents
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Kariyone,Kanno,Sugino
, (1937)
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Preparation method of butylphthalide and pharmaceutical intermediate thereof
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, (2018/11/03)
The present invention provides a new pharmaceutical intermediate and a method for preparing butylphthalide by using the new pharmaceutical intermediate. According to the method, o-phthalic acid monoester as a raw material and valerate are subjected to ester condensation, o-pentanoylbenzoic acid is prepared through hydrolysis and decarboxylation, and reducing with sodium borohydride and ring closure are performed to obtain the product. According to the present invention, the method has characteristics of inexpensive and easily-available raw material, mild reaction condition, no high-temperaturereaction, no Grignard reaction, production energy consumption reducing, production cost reducing and operation safety improving.
Ruthenium-Catalyzed Enantioselective Hydrogenation/Lactonization of 2-Acylarylcarboxylates: Direct Access to Chiral 3-Substituted Phthalides
Lu, Bin,Zhao, Mengmeng,Ding, Guangni,Xie, Xiaomin,Jiang, Lili,Ratovelomanana-Vidal, Virginie,Zhang, Zhaoguo
, p. 3989 - 3996 (2017/09/13)
Highly enantioselective tandem hydrogenation/lactonization of various 2-acylarylcarboxylates including 2-aroylarylcarboxylates were realized by using [RuCl(benzene)(S)-SunPhos]Cl as the catalyst under mild reaction conditions. Excellent enantioselectivities (up to 99.6 % ee) and activities (S/C=1000) were obtained. This convenient and practical method enables a direct access to a series of highly optically pure 3-substituted phthalides that are very important molecules as valuable pharmacological compounds and diversified synthons for medicinal chemistry. Moreover, a gram-scale reaction was performed to further demonstrate the practicality of this approach.
