55000-02-7Relevant articles and documents
Identification of small molecules that inhibit GSK-3β through virtual screening
Kang, Nam Sook,Lee, Gil Nam,Kim, Chi Hyun,Bae, Myung Ae,Kim, Ikyon,Cho, Young Sik
scheme or table, p. 533 - 537 (2011/03/20)
Glycogen synthase kinase-3β (GSK-3β) is involved in glycogen metabolism, neuronal cell development, osteoblast differentiation. Small molecule inhibitors of GSK-3β have various therapeutic potential for the treatment of diabetes type II, bipolar disorders
First non-ATP competitive glycogen synthase kinase 3 β (GSK-3β) inhibitors: Thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease
Martinez, Ana,Alonso, Mercedes,Castro, Ana,Pérez, Concepción,Moreno, Francisco J.
, p. 1292 - 1299 (2007/10/03)
Glycogen synthase kinase 3 β (GSK-3β) has a central role in Alzheimer′s disease (AD). Selective inhibitors which avoid τ hyperphosphorylation may represent an effective therapeutical approach to the AD pharmacotherapy and other neurodegenerative disorders