5501-39-3

Basic information

• Product Name: 3-acetyl-4-hydroxy-6-methyl-2-pyridone
• Synonyms: 3-acetyl-4-hydroxy-6-methyl-2-pyridone;3-Acetyl-4-hydroxy-6-methyl-2(1H)-pyridinone;3-Acetyl-4-hydroxy-6-Methylpyridin-2(1H)-one
• CAS NO: 5501-39-3
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16196
• EINECS: 226-837-3
• Mol File: 5501-39-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 324.4°Cat760mmHg
• Flash Point: 150°C
• Appearance: /
• Density: 1.308g/cm³
• Vapor Pressure: 1.92E-05mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-acetyl-4-hydroxy-6-methyl-2-pyridone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-acetyl-4-hydroxy-6-methyl-2-pyridone(5501-39-3)
• EPA Substance Registry System: 3-acetyl-4-hydroxy-6-methyl-2-pyridone(5501-39-3)

Safety Data

• Hazardous Substances Data: 5501-39-3(Hazardous Substances Data)

Usage

General Description

3-acetyl-4-hydroxy-6-methyl-2-pyridone is a chemical compound with a molecular formula C8H9NO3. It is a derivative of the pyridone ring and is found in natural sources such as soil bacteria as well as in synthetic forms. The compound has been reported to exhibit antioxidant and anti-inflammatory properties, making it potentially useful in pharmaceutical and cosmeceutical applications. Additionally, 3-acetyl-4-hydroxy-6-methyl-2-pyridone has shown potential for use in the treatment of neurodegenerative diseases and as a chelating agent for metal ions. Further research is needed to fully understand its potential uses and applications.

InChI:InChI=1/C8H9NO3/c1-4-3-6(11)7(5(2)10)8(12)9-4/h3H,1-2H3,(H2,9,11,12)

Upstream product

• 5977-14-0 acetoacetamido 
• 5394-63-8 2,2,6-trimethyl-4H-1,3-dioxin-4-one 
• 77287-34-4 formamide 
• 82437-52-3 N-formylacetoacetamide 
• 35287-94-6 4-hydroxy-7-methyl-2H-pyrano[3,2-c]pyridine-2,5(6H)-dione 
• 3749-51-7 4-hydroxy-6-methyl-2-pyridone 

Downstream Products

• 70542-09-5 2-(4-methoxy-phenyl)-7-methyl-2,3-dihydro-6H-pyrano[3,2-c]pyridine-4,5-dione 
• 7211-76-9 4-hydroxy-6-methyl-3-[(1E)-N-phenylethanehydrazonoyl]pyridine-2(1H)-one 
• 70542-14-2 6-bromo-2-(4-methoxy-phenyl)-7-methyl-6H-pyrano[3,2-c]pyridine-4,5-dione 
• 70542-11-9 2-(4-methoxy-phenyl)-7-methyl-6H-pyrano[3,2-c]pyridine-4,5-dione 
• 79039-83-1 2,4-dichloro-3-ethynyl-6-methylpyridine 
• 79039-84-2 2,4-dichloro-3-(1-chlorovinyl)-6-methylpyridine 

Relevant articles and documents

Studies on ketene and its derivatives. XII. The structure of the self-condensation product of acetoacetamide.

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Synthesis of N-Acylacetoacetamide using 2,2,6-Trimethyl-1,3-dioxin-4-one

Diketene-acetone adduct (2,2,6-trimethyl-1,3-dioxin-4-one) 1 reacts with amide NH to give the corresponding N-acetoacetates 2.Formamide and basic amides such as picolinamide, on treatment with the adduct, are transformed to the N-acyl-2,6-dimethyl-4-oxo-4H-pyran-3-carboxamide (4a and 4p) together with the corresponding N-acetoacetates.Keywords--diketene-acetone adduct; 1,3-dioxin-4-one; acetylketene; diketene; acetoacetylation; 4-pyrone derivatives; N-acylacetoacetamide

Synthetic studies of azaflavonoids. II. Synthesis of 6-azaflavonoids

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