55022-23-6

Basic information

• Product Name: 2-(1-methylpyridin-2(1H)-ylidene)-1H-indene-1,3(2H)-dione
• CAS NO: 55022-23-6
• Molecular Formula: C₁₅H₁₁NO₂
• Molecular Weight: 237.2533
• Mol File: 55022-23-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 404.6°C at 760 mmHg
• Flash Point: 187.7°C
• Density: 1.328g/cm³
• Vapor Pressure: 9.3E-07mmHg at 25°C
• Refractive Index: 1.672
• CAS DataBase Reference: 2-(1-methylpyridin-2(1H)-ylidene)-1H-indene-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-methylpyridin-2(1H)-ylidene)-1H-indene-1,3(2H)-dione(55022-23-6)
• EPA Substance Registry System: 2-(1-methylpyridin-2(1H)-ylidene)-1H-indene-1,3(2H)-dione(55022-23-6)

Safety Data

• Hazardous Substances Data: 55022-23-6(Hazardous Substances Data)

Usage

Appearance

Yellow solid

Usage

Organic synthesis, reagent for chemical reactions

Industries

Pharmaceutical, agrochemical

Biological activities

Antioxidant, anti-inflammatory properties

Therapeutic potential

Compound of interest for potential therapeutic applications

Fluorescent properties

Demonstrated potential as a fluorescent dye

Research applications

Imaging and labeling in biological and chemical research

Upstream product

• 109-06-8 α-picoline 
• 131-11-3 phthalic acid dimethyl ester 
• 63542-24-5 2-(1H-pyridin-2-ylidene)-indan-1,3-dione 
• 74-88-4 methyl iodide 
• 606-23-5 1H-indene-1,3(2H)-dione 
• 120879-63-2 2-iodo-1-methyl-pyridinium 
• 186581-53-3 diazomethane 

Relevant articles and documents

Synthesis and pharmacological evaluation of 2-(2 and 4- pyridinyl)indane-1,3-diones and structuraly related compounds exerting potential anti-inflammatory and antitumoral activities

Our on going work in the series of enamido-diketones issued from 2- azaarylindane-1,3-diones led us to synthesize and experiment N and C2- substituted derivatives of 2-(2 and 4-pyridinyl)indane-1,3-diones as well as of structurally related compounds resulting from the replacement of pyridine by quinoline and benzimidazole. Pharmacological evaluation of their anti- inflammatory activity (by inhibition of carrageenan foot edema) and their anticoagulant activity (by prothombin assay) led to the conclusion of the possibility of achieving a selective antiinflammatory effect. It has been previously established that anticoagulants are liable to exert a protective effect in the development of cancer metastasis. Nevertheless none of the six experimented 2-(pyridin-2-yl)indane-1,3-diones extended survival time of mice treated by P388 lymphocytic leukemia.