550369-44-3

Basic information

• Product Name: 4-Piperidinol, 4-ethyl-
• Synonyms: 4-ethylpiperidin-4-ol
• CAS NO: 550369-44-3
• Molecular Formula: C₇H₁₅NO
• Molecular Weight: 129.2
• Mol File: 550369-44-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 204.8±15.0 °C(Predicted)
• Appearance: /
• Density: 0.953±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 15.01±0.20(Predicted)
• CAS DataBase Reference: 4-Piperidinol, 4-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinol, 4-ethyl-(550369-44-3)
• EPA Substance Registry System: 4-Piperidinol, 4-ethyl-(550369-44-3)

Safety Data

• Hazardous Substances Data: 550369-44-3(Hazardous Substances Data)

Usage

General Description

4-Piperidinol, 4-ethyl- is a chemical compound with the molecular formula C8H17NO. It is a derivative of piperidine and is classified as a tertiary amine. 4-Piperidinol, 4-ethyl- is commonly used as a building block in the synthesis of various pharmaceuticals and other organic compounds. It is also used in the manufacture of certain agrochemicals and as a solvent in the production of resins and dyes. Additionally, 4-Piperidinol, 4-ethyl- is known to have some medicinal properties and has been studied for its potential as an analgesic and anticonvulsant. However, it is important to handle this chemical with care, as it can be toxic and should only be used by trained professionals in a controlled laboratory setting.

Upstream product

• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 
• 440101-11-1 1-benzyl-4-ethyl-4-hydroxypiperidine 
• 3612-20-2 1-phenylmethyl-4-piperidone 

Downstream Products

• 1374855-92-1 (E)-3-(4-chlorophenyl)-N-(2-(4-ethyl-4-hydroxypiperidin-1-yl)-4-methylquinazolin-6-yl)acrylamide 
• 1429504-80-2 (4-ethyl-4-hydroxypiperidin-1-yl)(5-methyl-2-(pyridin-4-yl)-phenyl)methanone 
• 1374567-37-9 C₂₄H₂₇ClN₄O₃ 

Relevant articles and documents

Design, synthesis, and in vitro bioactivity evaluation of fluorine-containing analogues for sphingosine-1-phosphate 2 receptor

Twenty eight new aryloxybenzene analogues were synthesized and their in vitro binding potencies toward S1PR2 were determined using a [32P]S1P competitive binding assay. Out of these new analogues, three compounds, 28c (IC50 = 29.9 ± 3.9 nM), 28e (IC50 = 14.6 ± 1.5 nM), and 28g (IC50 = 38.5 ± 6.3 nM) exhibited high binding potency toward S1PR2 and high selectivity over the other four receptor subtypes (S1PR1, 3, 4, and 5; IC50 > 1000 nM). Each of the three potent compounds 28c, 28e, and 28g contains a fluorine atom that will allow to develop F-18 labeled PET radiotracers for imaging S1PR2.

Benzimidazolidinone derivatives as muscarinic agents

Benzimidazolidinone derivative compounds, which increase acetylcholine signaling or effect in the brain, and highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor subtypes, pharmaceutical compositions comprising the same, as well as methods of treating psychosis using these compounds are disclosed.