55094-77-4

Basic information

• Product Name: (1E,6E)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione
• Synonyms: (1E,6E)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione
• CAS NO: 55094-77-4
• Molecular Weight: 396.44
• Mol File: 55094-77-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (1E,6E)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (1E,6E)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione(55094-77-4)
• EPA Substance Registry System: (1E,6E)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione(55094-77-4)

Safety Data

• Hazardous Substances Data: 55094-77-4(Hazardous Substances Data)

Upstream product

• 458-37-7 curcumin 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 
• 458-37-7 curcumin 
• 123-54-6 acetylacetone 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Relevant articles and documents

Synthesis and anti-inflammatory properties of some aromatic and heterocyclic aromatic curcuminoids

A variety of novel aromatic and heterocyclic aromatic curcuminoids were synthesised, characterised and their anti-inflammatory activities (AIA) determined in vivo. Some of these compounds also were tested for inflammatory mediator production. The AIA of t

A PERSONAL CARE COMPOSITION COMPRISING CURCUMINOIDS

The invention relates to a personal care composition comprising a compound of the curcuminoid class and to a process of preparing it. It has been shown to have anti-inflammatory benefit and can be utilised in a wide range of personal care products, while

Reactions of reactive oxygen species (ROS) with curcumin analogues: Structure-activity relationship

Three curcumin analogues viz., bisdemethoxy curcumin, monodemethoxy curcumin, and dimethoxycurcumin that differ at the phenolic substitution were synthesized. These compounds have been subjected for free radical reactions with DPPH radicals, superoxide radicals (O2?-?), singlet oxygen (1O2) and peroxyl radicals (CCl3O2 ?) and the bimolecular rate constants were determined. The DPPH radical reactions were followed by stopped-flow spectrometer, 1O2 reactions by transient luminescence spectrometer, and CCl3O 2? reactions using pulse radiolysis technique. The rate constants indicate that the presence of o-methoxy phenolic OH increases its reactivity with DPPH and CCl3O2?, while for molecules lacking phenolic OH, this reaction is very sluggish. Reaction of O2?-? and 1O2 with curcumin analogues takes place preferably at β-diketone moiety. The studies thus suggested that both phenolic OH and the β-diketone moiety of curcumin are involved in neutralizing the free radicals and their relative scavenging ability depends on the nature of the free radicals.