55109-51-8

Basic information

• Product Name: N-(4-nitrophenyl)-2-oxo-2-phenylacetamide
• Synonyms: N-(4-nitrophenyl)-2-oxo-2-phenylacetamide
• CAS NO: 55109-51-8
• Molecular Weight: 270.244
• Mol File: 55109-51-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-(4-nitrophenyl)-2-oxo-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-nitrophenyl)-2-oxo-2-phenylacetamide(55109-51-8)
• EPA Substance Registry System: N-(4-nitrophenyl)-2-oxo-2-phenylacetamide(55109-51-8)

Safety Data

• Hazardous Substances Data: 55109-51-8(Hazardous Substances Data)

Upstream product

• 107098-81-7 N¹,N¹-Dimethyl-N²-(4-nitrophenyl)-2-(4-nitrophenylimino)-2-phenylacetamidin 
• 4604-65-3 1-dimethylamino-2-phenyl-ethyne 
• 122-78-1 phenylacetaldehyde 
• 100-01-6 4-nitro-aniline 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 1074-12-0 phenylglyoxal hydrate 
• 15148-19-3 1,3-bis(p-nitrophenyl)-2-thia-1,3-diazaallene 
• 25726-04-9 phenylglyoxylyl chloride 
• 107098-77-1 N¹,N¹-Dimethyl-N²-(4-nitrophenyl)-2-(4-nitrophenylimino-λ⁴-sulfanyliden)-2-phenylacetamidin 
• 4485-08-9 4-nitrosonitrobenzene 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 103-80-0 phenylacetyl chloride 
• 13140-77-7 N-(4-nitrophenyl)-2-phenylacetamide 

Relevant articles and documents

IronO-Catalyzed Domino Aerobic Alcohol Oxidation/Oxidative Cross-Dehydrogenative Coupling for the Synthesis of α-Keto Amides

An ironO-catalyzed (TEMPO = 2,2,6,6-tetramethyl-1-piperidinyloxy), aerobic process was developed to synthesize α-keto amides. This reaction proceeds through a domino alcohol oxidation/oxidative cross-dehydrogenative coupling sequence, uses 2-hydroxyacetophenones and amines as the starting materials, and takes place under molecular oxygen, which makes the transformation highly efficient, practical, and environmentally friendly.

Copper-catalyzed aerobic oxidative cross-dehydrogenative coupling of amine and α-carbonyl aldehyde: A practical and efficient approach to α-ketoamides with wide substrate scope

A copper-catalyzed aerobic oxidative cross-dehydrogenative coupling (CDC) of amine with α-carbonyl aldehyde has been developed. Many types of amines are tolerant in this transformation leading to various α-ketoamides compounds. Wide substrate scope, CDC strategy and using air as oxidant make this transformation highly efficient and practical. Molecular oxygen acts not only as the oxidant, but also as an initiator to trigger this catalytic process. Furthermore, mechanism studies show that carbonyl group of α-carbonyl aldehyde plays a role as the directing group to facilitate this chemical process.

Copper-catalyzed aerobic oxidative coupling of aryl acetaldehydes with anilines leading to α-ketoamides

Efficient and practical: The title reaction provides an efficient route to α-ketoamides compounds, which are ubiquitous structural units in a number of biologically active compounds. N-substituted anilines are suitable substrates for this transformation.