55160-66-2

Basic information

• Product Name: 4-(2-chloroethyl)thiomorpholine1,1-dioxide
• Synonyms: EOS-60874
• CAS NO: 55160-66-2
• Molecular Formula: C₆H₁₂ClNO₂S
• Molecular Weight: 197.68298
• Mol File: 55160-66-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2-chloroethyl)thiomorpholine1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-chloroethyl)thiomorpholine1,1-dioxide(55160-66-2)
• EPA Substance Registry System: 4-(2-chloroethyl)thiomorpholine1,1-dioxide(55160-66-2)

Safety Data

• Hazardous Substances Data: 55160-66-2(Hazardous Substances Data)

Usage

Structure

Thiomorpholine ring with a sulfur atom and a chloroethyl group attached, along with a morpholine-1,1-dioxide group.

Industrial Use

Used in the pharmaceutical industry as a building block for synthesizing various drugs, especially anticancer agents.

Organic Chemistry

Employed as a reagent for modifying other molecules in organic synthesis.

Toxicity

Known for potential mutagenic and carcinogenic effects.

Safety Precautions

Proper handling and safety measures are crucial when working with this compound.

Upstream product

• 26475-62-7 4-(2-hydroxyethyl)thiomorpholine 1,1-dioxide 

Downstream Products

• 1449661-64-6 methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-((2-(1,1-dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)cyclohex-3-enecarboxylate 
• 1392315-15-9 methyl 4-[(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-[[2-(1,1-dioxido-4-thiomorpholinyl)ethyl]amino]-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-5a,5b,8,8,11a-pentamethyl-1-(1-methylethenyl)-1Hcyclopenta[a]chrysen-9-yl]-2-fluoro-benzoate 
• 1392314-60-1 methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-((2-(1,1-dioxido-4-thiomorpholinyl)ethyl)amino)-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate 

Relevant articles and documents

C-3 NOVEL TRITERPENE WITH C-17 AMINE DERIVATIVES AS HIV INHIBITORS

The present invention relates to to C-3 novel triterpene with C-17 amine derivatives of formula (I); or pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, prodrugs, compositions or combination thereof, wherein R1, R2, R3, R4, R5 and 'n' are as defined herein. The present invention also relates to pharmaceutical compositions comprising compounds of formula (I) and process for preparing them, and their use for the treatment of viral diseases and particularly HIV mediated diseases.