552-37-4

Basic information

• Product Name: SODIUM ANTHRANILATE
• Synonyms: Benzoicacid,2-amino-,monosodiumsalt;Natrium-2-aminobenzoat;SODIUM 2-AMINOBENZOATE;SODIUM ANTHRANILATE;SODIUM ANTHRANILATE N-HYDRATE;2-AMINOBENZOIC ACID SODIUM SALT;ANTHRANILIC ACID SODIUM SALT;Anthralinicacidsodiumsalt
• CAS NO: 552-37-4
• Molecular Formula: C₇H₆NO₂*Na
• Molecular Weight: 159.12
• EINECS: 209-010-1
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 552-37-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: <250 °C
• Boiling Point: 311.9°Cat760mmHg
• Flash Point: 142.4°C
• Appearance: /
• Density: 1.315g/cm³
• Vapor Pressure: 0.000234mmHg at 25°C
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: SODIUM ANTHRANILATE(CAS DataBase Reference)
• NIST Chemistry Reference: SODIUM ANTHRANILATE(552-37-4)
• EPA Substance Registry System: SODIUM ANTHRANILATE(552-37-4)

Safety Data

• Hazardous Substances Data: 552-37-4(Hazardous Substances Data)

Usage

Description

SODIUM ANTHRANILATE, also known as 2-Aminobenzoic Acid Sodium Salt, is a chemical compound with the CAS number 552-37-4. It is characterized by its unique chemical structure and properties, making it a versatile substance with various applications across different industries.

Uses

Used in Pharmaceutical Industry:
SODIUM ANTHRANILATE is used as a reagent for the preparation of benzisoxazolones, which are important intermediates in the synthesis of various pharmaceutical compounds. The application reason is its ability to facilitate the formation of these intermediates, contributing to the development of new drugs and therapies.
Used in Chemical Synthesis:
In the field of chemical synthesis, SODIUM ANTHRANILATE is used as a building block for the creation of various organic compounds. Its application reason lies in its reactivity and compatibility with other chemical groups, allowing for the formation of a wide range of products with diverse applications.
Used in Research and Development:
SODIUM ANTHRANILATE is also utilized in research and development settings, where it serves as a valuable tool for studying the properties and reactions of aminobenzoic acid derivatives. The application reason is its potential to provide insights into the behavior of similar compounds, leading to advancements in the understanding of chemical reactions and the development of new materials and applications.

InChI:InChI=1/C7H7NO2.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4H,8H2,(H,9,10);/q;+1/p-1

Upstream product

• 136918-14-4 phthalimide 
• 118-92-3 anthranilic acid 

Downstream Products

• 121845-92-9 2-<2-nitroethylideneamino>benzoic acid 
• 124188-04-1 N-(1H-tetrazol-5-yl)-N'-(2-carboxyphenyl)formamidine, sodium salt 
• 5252-93-7 2-[(Z)-(3-Phenyl-acryloyl)amino]-benzoic acid 2-dimethylamino-ethyl ester 
• 118-92-3 anthranilic acid 
• 5326-47-6 2-amino-5-iodobenzoic acid 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 609-85-8 2-amino-3,5-dibromobenzoic acid 

Relevant articles and documents

Di- and triorganotin(IV) complexes of 2-aminobenzoic acid with and without triphenylphosphine: Synthesis, spectroscopy, semi-empirical study, and antimicrobial activities

Eight organotin carboxylates have been synthesized in quantitative yield by reaction of NaL (L = 2-aminobenzoate) with the di- and triorganotin chlorides and triphenylphosphine. All the complexes have been characterized by elemental analysis, IR, multinuclear NMR (1H, 13C, and 119Sn), and mass spectrometry. The spectroscopic data indicate 1 : 2/1 : 1 M : L stoichiometry in 1, 3, 5, and 7 and 1 : 2 : 1/1 : 1 : 1 M : L : PPh3 stoichiometry in 2, 4, 6, and 8. FT-IR spectra clearly demonstrate metal attachment with both oxygens of the ligand and bidentate coordination in 1, 3, 5, and 7 while monodentate ligand for 2, 4, 6, and 8. In solid state, 1, 2, 5, and 6 exhibit six coordination whereas 3, 4, 7, and 8 show five coordination. The structural behavior is confirmed by semi-empirical study. NMR data reveal four-coordinate geometry in solution. These complexes were screened for antimicrobial activity invitro. The screening tests show that tributyltin carboxylates are more potent antibacterial and fungicidal agents than corresponding methyl derivatives, and triphenylphosphine enhances the antibacterial and fungicidal activities of these complexes.

Anti-inflammatory and anti-ulcer compounds and process

Disclosed herein are anti-inflammatory and anti-ulcer copper coordination compounds and a process for using them in the treatment of arthritis and gastrointestinal ulcers in animal bodies. The copper coordination compounds utilized are the reaction products of copper salts with: 1. aromatic carboxylic acids or their alkaline earth salts; 2. heterocyclic carboxylic acids or their alkaline earth salts; 3. amino acids or their alkaline earth salts; 4. amines; and 5. suitably substituted steroids. The process disclosed comprises administering to experimental animals, orally or parentrally (subcutaneously), in controlled dosages, the aforementioned copper coordination compounds for the treatment of inflammation (i.e., arthritis) and ulcers of the gastrointestinal tract.