55216-11-0 Usage
Description
TRIMETHYL-BETA-CYCLODEXTRIN, also known as Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin, is a β-cyclodextrin derivative with a non-polar cavity that makes it an attractive molecular host for a wide range of molecules. It is known for its affinity for organic compounds in both solution and crystalline phases, making it a versatile compound with potential applications in various industries.
Uses
Used in Pharmaceutical Applications:
TRIMETHYL-BETA-CYCLODEXTRIN is used as a solubilizing agent for steroids in aqueous solutions to increase their bioavailability.
Used in Research and Analysis:
TRIMETHYL-BETA-CYCLODEXTRIN is used as a complexing agent to investigate the crystal structure of its complexes with various compounds, such as m-iodophenol, 4-biphenylacetic acid, and (R)and (S)-flurbiprofen, through X-ray analysis.
Used in Drug Delivery Systems:
TRIMETHYL-BETA-CYCLODEXTRIN is used as a component in the development of drug delivery systems, particularly for ophthalmic applications. Its complex with vitamin A is studied for potential use in high sensitivity fluorescence spectrometry and high pressure liquid chromatography (HPLC) techniques.
Used in Quality Control and Analysis:
TRIMETHYL-BETA-CYCLODEXTRIN is used in the determination of analyte composition in commercial samples through high performance liquid chromatography (HPLC) coupled to mass spectrometry (MS).
Used in Food Industry:
TRIMETHYL-BETA-CYCLODEXTRIN is used as an additive in the food industry to improve the solubility and stability of certain ingredients, as well as to enhance flavor and texture.
Used in Cosmetic Applications:
TRIMETHYL-BETA-CYCLODEXTRIN is used in the cosmetic industry for its ability to complex with and stabilize various compounds, improving the performance and efficacy of cosmetic products.
Check Digit Verification of cas no
The CAS Registry Mumber 55216-11-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,2,1 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 55216-11:
(7*5)+(6*5)+(5*2)+(4*1)+(3*6)+(2*1)+(1*1)=100
100 % 10 = 0
So 55216-11-0 is a valid CAS Registry Number.
InChI:InChI=1/C63H112O35/c1-64-22-29-36-43(71-8)50(78-15)57(85-29)93-37-30(23-65-2)87-59(52(80-17)44(37)72-9)95-39-32(25-67-4)89-61(54(82-19)46(39)74-11)97-41-34(27-69-6)91-63(56(84-21)48(41)76-13)98-42-35(28-70-7)90-62(55(83-20)49(42)77-14)96-40-33(26-68-5)88-60(53(81-18)47(40)75-12)94-38-31(24-66-3)86-58(92-36)51(79-16)45(38)73-10/h29-63H,22-28H2,1-21H3/t29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43+,44+,45+,46+,47+,48+,49+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m1/s1
55216-11-0Relevant articles and documents
Synthesis of cyclodextrins with carboxylic acids at the secondary rim and an evaluation of their properties as chemzymes for glycoside hydrolysis
Zhou, You,Lindbaeck, Emil,Marinescu, Lavinia G.,Pedersen, Christian Marcus,Bols, Mikael
, p. 4063 - 4070 (2012)
Seven β-cyclodextrin-mono-, -di-or -tetra-O-acetic acids were prepared and investigated for their propertiesas catalysts of the hydrolysis of four nitrophenyl glycosides.
A facile synthesis of novel cyclodextrin derivatives incorporating one beta-(1,4)-glucosidic bond and their unique inclusion ability.
Kida, Toshiyuki,Kikuzawa, Akira,Nakatsuji, Yohji,Akashi, Mitsuru
, p. 3020 - 3021 (2003)
Novel cyclodextrin derivatives incorporating one (1,4)-glucosidic bond are easily synthesized in three steps from permethylated alpha- and beta-cyclodextrins, and such host molecules show inclusion selectivity for sodium m-nitrobenzoate over the corresponding p-isomer, in contrast to the cases of the parent permethylated alpha- and beta-cyclodextrins.
Xylylene Clips for the Topology-Guided Control of the Inclusion and Self-Assembling Properties of Cyclodextrins
Neva, Tania,Carmona, Thais,Benito, Juan M.,Przybylski, Cédric,Ortiz Mellet, Carmen,Mendicuti, Francisco,García Fernández, José M.
, p. 5588 - 5597 (2018)
The topology of β-cyclodextrin can be molded, from toroidal to ovoid basket-shaped, by the installation of an o- or m-xylylene moiety connecting two consecutive d-glucopyranosyl units through the secondary O-2(I) and O-3(II) positions. This strategy can be exploited advantageously to precast the cavity for preferential inclusion of globular or planar guests as well as to privilege dimeric or monomeric species in water solution.
Enhanced photodynamic therapy through supramolecular photosensitizers with an adamantyl-functionalized porphyrin and a cyclodextrin dimer
Xia, Lei,Wu, Jian,Huang, Baoxuan,Gao, Yun,Tian, Jia,Zhang, Weian
supporting information, p. 11134 - 11137 (2020/10/05)
A supramolecular photosensitizer was constructed using a tetra-adamantane-functionalized porphyrin and a dimer of permethyl-β-cyclodextrin through host-guest interaction and self-assembly. The porphyrin/cyclodextrin alternating structure of supramolecular
