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55287-62-2

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55287-62-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 55287-62-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,2,8 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 55287-62:
(7*5)+(6*5)+(5*2)+(4*8)+(3*7)+(2*6)+(1*2)=142
142 % 10 = 2
So 55287-62-2 is a valid CAS Registry Number.

55287-62-2Downstream Products

55287-62-2Relevant articles and documents

Effects of lipid chain lengths in α-galactosylceramides on cytokine release by natural killer T cells

Goff, Randal D.,Gao, Ying,Mattner, Jochen,Zhou, Dapeng,Yin, Ning,Cantu III, Carlos,Teyton, Luc,Bendelac, Albert,Savage, Paul B.

, p. 13602 - 13603 (2004)

Glycolipid presentation by CD1 proteins has emerged as an important aspect of antigen recognition, and presentation of α-glycosylceramides by CD1d to natural killer T cells has become a central focus in understanding how glycolipid presentation can influence immune responses. An α-galactosylceramide containing relatively long lipid chains has been the subject of intense study because, when presented by CD1d to natural killer T cells, it stimulates the release of both proinflammatory and immunomodulatory cytokines. Using an efficient synthesis of α-galactosylceramides, we have prepared a series of glycolipids in which the lipid chain lengths have been incrementally varied. The responses of natural killer T cells to these glycolipids have been determined, and we have found that truncation of the phytosphingosine lipid chain increases the relative amounts of immunomodulatory cytokines released. In similar fashion, the length of the acyl chain in α-galactosylceramides influences cytokine release profiles. Copyright

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