55297-96-6 Usage
Description
Tiamulin fumarate is a semisynthetic pleuromutilin antibiotic that is derived from Pleuromutilin and functions as an effective antibacterial agent. It is characterized by its white solid appearance and solubility in organic solvents such as ethanol, DMSO, and dimethyl formamide. Tiamulin fumarate is particularly potent and selective against a range of Gram-positive bacteria and mycoplasma species, with its unique mode of action involving the inhibition of protein synthesis by binding to the ribosomal peptidyl transferase center. This distinctive mechanism results in no cross-resistance to existing antibiotic classes, making it a valuable addition to the arsenal of antibiotics.
Uses
Used in Pharmaceutical Industry:
Tiamulin fumarate is used as an antibiotic for the treatment of bacterial infections caused by Gram-positive bacteria and certain mycoplasma species. Its application is particularly beneficial due to its high selectivity and lack of cross-resistance with other antibiotic classes, which addresses the growing concern of antibiotic resistance.
Used in Veterinary Medicine:
In the veterinary field, Tiamulin fumarate is utilized as an antimicrobial agent for the prevention and treatment of bacterial infections in animals. Its effectiveness against a variety of Gram-positive bacteria makes it a suitable choice for maintaining the health of livestock and pets.
Used in Agricultural Applications:
Tiamulin fumarate is also employed in the agricultural sector, specifically for the treatment and control of bacterial infections in livestock. Its targeted action against specific bacterial strains helps in reducing the spread of infections and maintaining the overall health of the animals, contributing to the productivity and sustainability of the agricultural industry.
Used in Research and Development:
As a compound with a unique mode of action, Tiamulin fumarate is used in research and development for the study of antibiotic mechanisms, the development of new antimicrobial agents, and the investigation of resistance patterns in bacteria. This contributes to the advancement of medical and veterinary sciences, as well as the ongoing fight against antibiotic resistance.
Indications
Tiamulin fumarate is mainly used for Mycoplasma suis pneumonia, Haemophilus parasuis, infectious pleuropneumonia and dysentery caused by Treponema swine, and also for chronic respiratory tract of poultry, Mycoplasma pneumonia, infectious rhinitis, Escherichia coli, duck Infectious serositis.
Mode of action
Tiamulin fumarate is a bacteriostatic antibiotic belonging to the pleuromutilin class, which inhibit protein synthesis by targeting the 50S bacterial ribosomal subunit and binding to peptidyl transferase, the enzyme responsible for forming peptide bonds between amino acids.
Check Digit Verification of cas no
The CAS Registry Mumber 55297-96-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,2,9 and 7 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 55297-96:
(7*5)+(6*5)+(5*2)+(4*9)+(3*7)+(2*9)+(1*6)=156
156 % 10 = 6
So 55297-96-6 is a valid CAS Registry Number.
InChI:InChI=1/C28H47NO4S.C4H4O4/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28;5-3(6)1-2-4(7)8/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t19?,20-,22+,24-,25-,26+,27-,28-;/m0./s1
