55313-03-6

Basic information

• Product Name: Ethanone, 2-hydroxy-1-(2,4,6-trihydroxyphenyl)-
• Synonyms: Hydroxymethyl-(2,4,6-trihydroxyphenyl)-keton;1-(2',4',6'-trihydroxyphenyl)-2-hydroxyethanone;2-hydroxy-1-(2,4,6-trihydroxy-phenyl)-ethanone;2-Hydroxy-1-(2,4,6-trihydroxy-phenyl)-aethanon;Ethanone,2-hydroxy-1-(2,4,6-trihydroxyphenyl)
• CAS NO: 55313-03-6
• Molecular Formula: C8H8O5
• Molecular Weight: 184.149
• Mol File: 55313-03-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 226°C
• CAS DataBase Reference: Ethanone, 2-hydroxy-1-(2,4,6-trihydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-hydroxy-1-(2,4,6-trihydroxyphenyl)-(55313-03-6)
• EPA Substance Registry System: Ethanone, 2-hydroxy-1-(2,4,6-trihydroxyphenyl)-(55313-03-6)

Safety Data

• Hazardous Substances Data: 55313-03-6(Hazardous Substances Data)

Usage

Preparation

Preparation according to Hoesch reaction from phloroglucinol,with acetoxyacetonitrile (81%)with hydroxyacetonitrile (63%).

Upstream product

• 27200-12-0 ampelopsin 
• 108-73-6 3,5-dihydroxyphenol 
• 13157-89-6 2-(benzyloxy)-1-(2,4-bisbenzyloxy-6-hydroxyphenyl)ethanone 
• 99904-12-8 2-hydroxy-1-(2,4,6-trihydroxy-phenyl)-ethanone-imine; hydrochloride 
• 1001-55-4 2-acetoxyacetonitrile 

Downstream Products

• 480-18-2 taxifolin 
• 724434-08-6 dihydrokaempferol 
• 1580490-08-9 C₃₁H₃₇BrO₉ 
• 1642558-71-1 C₂₁H₁₅NO₆ 
• 1642558-70-0 2-(2-(3-hydroxyprop-1-yn-1-yl)-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl)acetonitrile 
• 1580489-97-9 C₁₉H₁₄O₆ 
• 1642558-73-3 C₁₈H₁₃NO₅ 
• 1642558-72-2 C₁₇H₁₁NO₅ 
• 1580489-94-6 C₁₆H₁₂O₅ 
• 1580490-11-4 C₃₉H₄₈O₁₁ 
• 1580489-98-0 C₂₃H₃₂O₈ 
• 117311-07-6 1-(2-hydroxy-4,6-bis-methanesulfonyloxy-phenyl)-2-methanesulfonyloxy-ethanone 

Relevant articles and documents

Taxifolin preparation method

The invention relates to a method for synthesizing a raw material medicine, in particular to a taxifolin preparation method, aiming to solve the technical problems that waste of plant resources and solvents is great during separation and purification of taxifolin from plants, complete synthesis methods of the taxifolin have long synthetic routes, many complicated raw ingredients are involved, theoverall yield is low and the methods are not suitable for industrial production in the prior art. The taxifolin preparation method has the advantages that dihydromyricetin is selected as a starting material, a crude taxifolin product is obtained by hydrolysis and catalysis closed-loop two-step reactions, and a qualified refined taxifolin product is obtained through purification and refining; the raw material is easy to obtain, the operation is simple, the cost is low, environment friendliness and small pollution are realized, and the taxifolin preparation method is suitable for industrial production.

Design, synthesis, and molecular docking study of flavonol derivatives as selective jak1 inhibitors

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