55417-34-0Relevant articles and documents
The total syntheses of JBIR-94 and two synthetic analogs and their cytotoxicities against A549 (CCL-185) human small lung cancer cells
Mangum, Cathy L.,Munford, Mica B.,Sam, Alyssa B.,Young, Sandra K.,Beales, Jeremy T.,Subedi, Yagya Prasad,Mangum, Chad D.,Allen, Tanner J.,Liddell, Miranda S.,Merrell, Andrew I.,Saavedra, Diana I.,Williams, Becky L.,Evans, Nicole,Beales, Joseph L.,Christiansen, Michael A.
supporting information, (2019/11/29)
We here disclose the total syntheses of the natural polyphenol JBIR-94 and two nonnatural analogs, whose structures are of interest for their bioactivity potential as radical scavengers. Although we initially attempted this by dually acylating both of putrecine's amine nitrogens in a single pot, our endeavors with this method (which has been successfully reported by other groups) proved ineffectual. We accordingly opted for the lengthier approach of acylating each amine individually, which gratuitously prevailed and also aligns with separate literature precedent. Moreover, we here share our analysis of these target compounds’ cytotoxicities and IC50 values against A549 (CCL-185) human small lung cancer cells.
Biorenewable polyethylene terephthalate mimics derived from lignin and acetic acid
Mialon, Laurent,Pemba, Alexander G.,Miller, Stephen A.
supporting information; experimental part, p. 1704 - 1706 (2011/01/12)
Lignin-based vanillin and acetic anhydride are subjected to the Perkin reaction and then hydrogenation to afford acetyldihydroferulic acid. Polymerization of this monomer yields poly(dihydroferulic acid), which exhibits thermal properties functionally similar to those of polyethylene terephthalate (PET).
γ-selective hydroxylation of α,β,γ,δ-unsaturated carbonyl compounds and its application to syntheses of (±)-6-hydroxyshogaol and related furanoids
Matsushita,Matsushita, Yoh-Ichi,Sugamoto,Sugamoto, Kazuhiro,Nakama,Nakama, Tuyoshi,Sakamoto,Sakamoto, Toshifumi,Matsui,Matsui, Takanao,Nakayama,Nakayama, Mitsuru
, p. 1879 - 1882 (2007/10/02)
α,β,γ,δ-Unsaturated carbonyl compounds were converted regioselectively into γ-hydroxy-α,β-unsaturated carbonyl compounds by reduction-oxygenation with molecular oxygen and triethylsilane in the presence of cobalt(II) porphyrin as a catalyst followed by treatment with trimethyl phosphite. (±)-Hydroxyshogaol and related furanoids isolated from ginger were synthesized via this method.
