55483-01-7Relevant articles and documents
Synthesis of demethylated nidulol via an intramolecular Michael reaction
Jimenez, Rogelio,Maldonado, Luis A.,Salgado-Zamora, Hector
, p. 1274 - 1281 (2010)
An expeditious synthesis of 5,7-dihydroxy-6-methylphthalide from open-chain precursors is described. The key intermediates, synthons 3 and 4, were readily obtained from accessible materials and were further transformed to a common precursor, a five-membered lactone derivative, via an intramolecular Michael addition. Lactone 2 was aromatised to the phthalide system under basic conditions. The process thus constitutes a formal synthesis of the phthalide framework.
Synthetic Confirmation of the Structure of the Lichen Benzyl Esters Alectorialic and Barbatolic Acids
Elix, John A.,Jayanthi, Vilas K.
, p. 1841 - 1850 (2007/10/02)
The total synthesis of methyl alectorialate (3) and methyl barbatolate (4) has been achieved, and the synthetic esters have been compared with naturally derived material.In addition alectorialin (decarboxylalectorialic acid) (5) and barbatolin (6) have be