55488-51-2 Usage
Description
Carbonochloridic acid, decyl ester, also known as Decyl chloroformate, is an n-alkyl chloroformate derivative that is synthesized by reacting decyl alcohol with triphosgene. It is a versatile compound with various applications in different industries.
Uses
Used in Pharmaceutical Industry:
Carbonochloridic acid, decyl ester is used as a reagent for the preparation of (S)-(+)-N-decoxycarbonyl-leucine, a chiral surfactant. This chiral surfactant is essential in the pharmaceutical industry for the synthesis of various drugs, particularly those requiring enantiomeric purity.
Used in Chemical Synthesis:
In the chemical synthesis industry, carbonochloridic acid, decyl ester is used to synthesize decyl chloride via decarboxylation in the presence of dimethylformamide. Decyl chloride is an important intermediate in the production of various chemicals and materials, such as surfactants, lubricants, and plasticizers.
Used in Research and Development:
Carbonochloridic acid, decyl ester is also utilized in research and development for the exploration of new chemical reactions and the synthesis of novel compounds. Its unique reactivity and properties make it a valuable tool for chemists in various fields, including organic chemistry, materials science, and pharmaceutical chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 55488-51-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,4,8 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 55488-51:
(7*5)+(6*5)+(5*4)+(4*8)+(3*8)+(2*5)+(1*1)=152
152 % 10 = 2
So 55488-51-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H21ClO2/c1-2-3-4-5-6-7-8-9-10-14-11(12)13/h2-10H2,1H3
55488-51-2Relevant articles and documents
Anti-HIV-Active Nucleoside Triphosphate Prodrugs
Jia, Xiao,Schols, Dominique,Meier, Chris
, p. 6003 - 6027 (2020/07/10)
We disclose a study on nucleoside triphosphate (NTP) analogues in which the γ-phosphate is covalently modified by two different biodegradable masking units and d4T as nucleoside analogue that enable the delivery of d4TTP with high selectivity in phosphate buffer (pH 7.3) and by enzyme-triggered reactions in human CD4+ T-lymphocyte CEM cell extracts. This allows the bypass of all steps normally needed in the intracellular phosphorylation. These TriPPPro-nucleotides comprising an acyloxybenzyl (AB; ester) or an alkoxycarbonyloxybenzyl (ACB; carbonate) in combination with an ACB moiety are described as NTP delivery systems. The introduction of these two different groups led to the selective formation of γ-(ACB)-d4TTPs by chemical hydrolysis and in particular by cell extract enzymes. γ-(AB)-d4TTPs are faster cleaved than γ-(ACB)-d4TTPs. In antiviral assays, the compounds are highly active against HIV-1 and HIV-2 in wild-type CEM/O cells and more importantly in thymidine kinase-deficient CD4+ T-cells (CEM/TK-).
